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Overview

  • Product nameAnti-IL1 beta antibodySee all IL1 beta primary antibodies ...
  • Description
    Rabbit polyclonal to IL1 beta
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MAEVPELASE MMAYYSGNED DLFFEADGPK QMKCSFQDLD LCPLDGGIQL) of Human IL1 beta (NP_000567).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive controlHela cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab104279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use a concentration of 1 µg/ml. Predicted molecular weight: 31 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionProduced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Sequence similaritiesBelongs to the IL-1 family.
  • DomainThe similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
  • Cellular localizationSecreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.

    • Target information above from: UniProt accession P01584 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        Catabolin antibodyH1 antibodyIL 1 antibody
        IL 1 beta antibodyIL-1 beta antibodyIL1 BETA antibodyIL1B antibodyIL1B_HUMAN antibodyIL1F2 antibodyInterleukin 1 beta antibodyInterleukin-1 beta antibodyOAF antibodyOTTHUMP00000162031 antibodyPreinterleukin 1 beta antibodyPro interleukin 1 beta antibody
      see all

    Anti-IL1 beta antibody images

    • Western blot - IL1 beta antibody (ab104279)
      Western blot - IL1 beta antibody (ab104279)
      Anti-IL1 beta antibody (ab104279) at 1 µg/ml + HeLa cell line lysate at 10 µg

      Predicted band size : 31 kDa
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-IL1 beta antibody(ab104279)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-IL1 beta antibody(ab104279)
      Immunohistochemistry of Human Macrophage Cells tissue at an antibody concentration of 25 µg/ml using anti-IL1B antibody (ab104279)

    References for Anti-IL1 beta antibody (ab104279)

    ab104279 has not yet been referenced specifically in any publications.

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