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Overview

  • Product nameAnti-IL1 beta antibodySee all IL1 beta primary antibodies ...
  • Description
    Rabbit polyclonal to IL1 beta
  • Specificityab24771 recognizes chicken Interleukin 1 beta (chIL-1beta), which shares homology with mammalian IL-1beta.
  • Tested applicationsWB, Functional Studies, ELISA more details
  • Species reactivity
    Reacts with: Chicken
  • Immunogen

    Recombinaint chicken IL-1

Properties

Applications

Our Abpromise guarantee covers the use of ab24771 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
Functional Studies
ELISA
  • Application notesELISA: Use at an assay dependent dilution. FuncS: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 29 kDa in HD-11 cell lysates transfected with chIL-1.
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionProduced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
    • Sequence similaritiesBelongs to the IL-1 family.
    • DomainThe similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
    • Cellular localizationSecreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.

      • Target information above from: UniProt accession P01584 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Alternative names
        Catabolin antibodyH1 antibodyHematopoietin 1 antibody
        IFN beta inducing factor antibodyIL 1 antibodyIL 1 beta antibodyIL 1B antibodyIL-1 beta antibodyIL1 BETA antibodyIL1B antibodyIL1B_HUMAN antibodyIL1F2 antibodyInterleukin 1 beta antibodyInterleukin 1 beta precursor antibodyInterleukin-1 beta antibodyLAF antibodyOAF antibodyOsteoclast activating factor antibodyOTTHUMP00000162031 antibodyPreinterleukin 1 beta antibodyPreinterleukin beta antibodyPro interleukin 1 beta antibody
      see all

    References for Anti-IL1 beta antibody (ab24771)

    ab24771 has not yet been referenced specifically in any publications.

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