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Overview

  • Product nameIL1 beta proteinSee all IL1 beta proteins and peptides ...
  • Protein descriptionRecombinant full length Dog IL1 beta produced in yeast; amino acids 115-266 (152aa), Predicted MWt 17.5kDa (Swiss-Prot Q28292).
  • Expression hostYeast

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab87391 is purified by Ion-exchange chromatography.
  • FormLyophilised:Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
  • Storage instructionsStore at -20°C. Stable for 12 months at -20°C
  • Storage bufferPreservative: None
    Constituents: 10% Trehalose, 1.0X PBS
  • Concentration information loading...
  • Sequence notesAAMQSVDCKL QDISHKYLVL SNSYELRALH LNGENVNKQV VFHMSFVHGD ESNNKIPVVL GIKQKNLYLS CVMKDGKPTL QLEKVDPKVY PKRKMEKRFV FNKIEIKNTV EFESSQYPNW YISTSQVEGM PVFLGNTRGG QDITDFTMEF SS
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab87391 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        CatabolinH1IL 1
        IL 1 betaIL-1 betaIL1 BETAIL1BIL1B_HUMANIL1F2Interleukin 1 betaInterleukin-1 betaOAFOTTHUMP00000162031Preinterleukin 1 betaPro interleukin 1 beta
      see all
  • FunctionProduced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
  • Sequence similaritiesBelongs to the IL-1 family.
  • DomainThe similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.
  • Cellular localizationSecreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.

    • Target information above from: UniProt accession P01584 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for IL1 beta protein (ab87391)

    ab87391 has not yet been referenced specifically in any publications.

    Publishing research using ab87391 ? Please let us know so that we can cite the reference in this datasheet

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