Anti-IL11 antibody (ab76589)

Overview

• Product nameAnti-IL11 antibodySee all IL11 primary antibodies ...
• Description
  Rabbit polyclonal to IL11
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Macaque Monkey
• Immunogen

  Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human IL11.

  Read Abcam's proprietary immunogen policy

  (Peptide available as ab90835.)

• Positive controlThis antibody gave a positive signal in Human Plasma Total Protein.

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: 1% BSA, PBS, pH 7.4
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Stem Cells
  • Hematopoietic Progenitors
  • Myeloid
  • Thrombocytic Lineage

  • Cancer
  • Tumor immunology
  • Cytokines
  • Interleukins

  • Cardiovascular
  • Angiogenesis
  • Cytokines
  • Interleukin

  • Immunology
  • Adaptive Immunity
  • B Cells
  • Non-CD

  • Immunology
  • Secreted Molecules
  • Other secreted molecules

  • Immunology
  • Innate Immunity
  • Cytokines
  • Interleukins

Applications

Target

• FunctionDirectly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
• Sequence similaritiesBelongs to the IL-6 superfamily.
• Cellular localizationSecreted.

Target information above from: UniProt accession P20809 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 3589 Human
  • Omim: 147681 Human
  • SwissProt: P20809 Human
  • Unigene: 467304 Human

• Alternative names
  Adipogenesis inhibitory factor antibodyAGIF antibodyIL 11 antibody

  IL-11 antibodyIL11 antibodyIL11_HUMAN antibodyInterleukin 11 antibodyInterleukin-11 antibodyOprelvekin antibody

  see all

Anti-IL11 antibody images

• 

  Western blot - IL11 antibody (ab76589)
  Anti-IL11 antibody (ab76589) at 1 µg/ml + Human Plasma Total Protein Lysate at 10 µg
  
  Secondary
  Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
  developed using the ECL technique
  
  Performed under reducing conditions.
  
  Predicted band size : 21 kDa
  Observed band size : 27 kDa (why is the actual band size different from the predicted?)
  Additional bands at : 105 kDa. We are unsure as to the identity of these extra bands.
  
  Exposure time : 15 minutes
• 

  Western blot
  Anti-IL11 antibody (ab76589) at 1 µg/ml + IL11 protein (Active) (ab73620) at 0.1 µg
  
  Secondary
  Goat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed (ab97080) at 1/5000 dilution
  developed using the ECL technique
  
  Performed under reducing conditions.
  
  Exposure time : 30 seconds