Overview
- Product nameAnti-IL13 antibody [A130D 12G5 1E4]See all IL13 primary antibodies ...
- DescriptionMouse monoclonal [A130D 12G5 1E4] to IL13
- SpecificityRecognizes recombinant and native rat IL 13
- Tested applicationsWB, ELISA, Flow Cyt, Dot Blot more details
- Species reactivityReacts with: Rat
- Immunogen
Recombinant full length protein (Rat)
- Positive controlFACS: intracellular IL 13 can be detected in PMA/ionophore-stimulated rat splenocytes
Properties
- FormLiquid
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
Constituents: PBS, pH 7.2 -
Concentration information loading... - PurityProtein G purified
- Purification notes>95% pure as determined by SDS-PAGE analysis. 0.22 micron sterile filtered.
- Clonality Monoclonal
- Clone numberA130D 12G5 1E4
- IsotypeIgG1
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab52538 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: 1/500 - 1/1000. Predicted molecular weight: 14 kDa. |
| ELISA | ELISA: Use at an assay dependent dilution. |
| Flow Cyt | Flow Cyt: Use 0.1-1µg for 106 cells. |
| Dot Blot | Dot: 1/500 - 1/1000. |
Target
- FunctionCytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
- Involvement in diseaseDefects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
- Sequence similaritiesBelongs to the IL-4/IL-13 family.
- Cellular localizationSecreted.
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Database links
- Entrez Gene: 116553 Rat
- SwissProt: P42203 Rat
- Unigene: 9921 Rat
Target information above from: UniProt accession
P35225
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- Allergic rhinitis antibodyALRH antibodyBHR 1 antibody
- BHR1 antibodyBronchial hyperresponsiveness 1 (bronchial asthma) antibodyIL 13 antibodyIL-13 antibodyIl13 antibodyIL13_HUMAN antibodyInterleukin 13 antibodyInterleukin-13 antibodyInterleukin13 antibodyMGC116786 antibodyMGC116788 antibodyMGC116789 antibodyNC30 antibodyP600 antibody
see all
References for Anti-IL13 antibody [A130D 12G5 1E4] (ab52538)
ab52538 has not yet been referenced specifically in any publications.
