Overview
Product nameIL13 proteinSee all IL13 proteins and peptides ...
Protein descriptionRecombinant Murine Interleukin-13 (IL13) ; a 12.3 kDa protein containing 111 amino acid residues.
Expression hostE. coli
Properties
Purity> 95
% by SDS-PAGE
Purification notes>98% by SDS-PAGE and HPLC analysis.
FormLyophilised:Centrifuge the vial prior to opening. Reconstitute in sterile distilled water to a concentration of 0.1-1.0 µg/µl (Note: Slow to dissolve).
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: None
Constituents: 10mM Sodium citrate, pH 4.0
Endotoxin level is <0.1 ng per µg of IL-13.
Concentration information loading...
Additional notesThe reconstituted solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or at –20°C for future use.
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab51919
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Application
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Notes |
| Functional Studies |
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| SDS-PAGE |
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Application notesBiological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of TF-1 cells was < 4.0 ng/ml, corresponding to a specific activity of > 2.5 x 105 units/mg.
SDS-PAGE: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Protein info
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Alternative names
Allergic rhinitisALRHBHR1
Bronchial hyperresponsiveness 1 (bronchial asthma)IL 13IL-13Il13IL13_HUMANInterleukin 13Interleukin-13MGC116786MGC116788MGC116789NC30P600
see all
FunctionCytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
Involvement in diseaseDefects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
Sequence similaritiesBelongs to the IL-4/IL-13 family.
Cellular localizationSecreted.
References for IL13 protein (ab51919)
ab51919
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
