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Overview

  • Product nameIL17 proteinSee all IL17 proteins and peptides ...
  • Protein descriptionRecombinant full length Cow IL17 (amino acids 22-153) produced in yeast; 132 amino acids, Predicted MWt 17.4kDa (Swiss-Prot Q687Y7).
  • Expression hostYeast
  • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab87905 is purified by Ion-exchange chromatography.
  • FormLyophilised:Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 10% Trehalose, 1X PBS
  • Concentration information loading...
  • Sequence notesKAGVIIPQSP GCPPTEDKNF PQHVRVNLNI VNRSTNSRRP TDYHKRSTSP WTLHRNEDPE RYPSVIWEAK CSHSGCINAE GKVDHHMNSV TIQQEILVLR RESQHCPHSF RLEKMLVAVG CTCVTPIVRH LA
  • Research Areas
  • Applications

    Our Abpromise guarantee covers the use of ab87905 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab43440.
  • Protein info

    • Alternative names
        CTLA 8CTLA-8CTLA8
        Cytotoxic T lymphocyte associated antigen 8Cytotoxic T lymphocyte associated protein 8Cytotoxic T lymphocyte associated serine esterase 8Cytotoxic T-lymphocyte-associated antigen 8IL 17AIL-17IL-17AIL17IL17_HUMANIL17AInterleukin 17 (cytotoxic T lymphocyte associated serine esterase 8)Interleukin 17AInterleukin-17AInterleukin17Interleukin17AOTTHUMP00000016597OTTMUSP00000046003
      see all
  • FunctionInduces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
  • Tissue specificityRestricted to activated memory T-cells.
  • Sequence similaritiesBelongs to the IL-17 family.
  • Post-translational
    modifications
    Found both in glycosylated and nonglycosylated forms.
  • Cellular localizationSecreted.
  • Target information above from: UniProt accession Q16552 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for IL17 protein (ab87905)

    ab87905 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"