Anti-IL2 Receptor beta antibody [5H4] (Phycoerythrin) (ab95585)

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Overview

  • Product name
    Anti-IL2 Receptor beta antibody [5H4] (Phycoerythrin)
    See all IL2 Receptor beta primary antibodies
  • Description
    Rat monoclonal [5H4] to IL2 Receptor beta (Phycoerythrin)
  • Host species
    Rat
  • Conjugation
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Rat myeloma cells transfected with a truncated mouse IL2 Receptor beta cDNA

  • Positive control
    • BALB/c splenocytes
  • General notes


    Binding of IL2 to IL2 receptor beta is not inhibited by the ab95585.

Properties

Applications

Our Abpromise guarantee covers the use of ab95585 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.125µg for 105-8 cells.

Target

  • Function
    Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
  • Sequence similarities
    Belongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 1 fibronectin type-III domain.
  • Domain
    The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • CD122 antibody
      • CD122 antigen antibody
      • High affinity IL 2 receptor beta subunit antibody
      • High affinity IL 2 receptor subunit beta antibody
      • High affinity IL-2 receptor subunit beta antibody
      • IL-2 receptor subunit beta antibody
      • IL-2R subunit beta antibody
      • IL-2RB antibody
      • IL15RB antibody
      • IL2 receptor antibody
      • IL2RB antibody
      • IL2RB_HUMAN antibody
      • Interleukin 2 receptor beta antibody
      • Interleukin-2 receptor subunit beta antibody
      • P70 75 antibody
      • P70-75 antibody
      • P7075 antibody
      • p75 antibody
      see all

    Images

    • Flow Cytometry - Anti-IL2 Receptor beta antibody [5H4] (Phycoerythrin) (ab95585)
      Flow Cytometry - Anti-IL2 Receptor beta antibody [5H4] (Phycoerythrin) (ab95585)
      Staining of BALB/c splenocytes with staining buffer (autofluorescence) (open histogram) or 0.125 µg of ab95585 (filled histogram). Total viable cells were used for analysis.

    References

    ab95585 has not yet been referenced specifically in any publications.

    Publishing research using ab95585? Please let us know so that we can cite the reference in this datasheet.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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