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Product name
Anti-IL22 Receptor Alpha antibody
See all IL22 Receptor Alpha products (4) ...
Description
Goat polyclonal to IL22 Receptor Alpha
Tested applications
ELISA, ICC, IHC-Fr, IHC-Pmore details
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide: DSGPEGTPDTVYSIEYKTYGERDWVAKK, corresponding to N terminal amino acids 42-70 of Human IL22 Receptor.
DSGPEGTPDTVYSIEYKTYGERDWVAKK
Positive control
Human spleen or tonsil.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: 140mM Sodium chloride, 10mM Potassium phosphate. pH 7.2
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Adapters >> Transmembrane
Immunology >> Innate Immunity >> Cytokines >> Interleukins
Immunology >> Innate Immunity >> Macrophage / Inflamm.
Applications
Show applications key
Our Abpromise guarantee covers the use of ab18568 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
ICC
IHC-Fr
- 2 Images
IHC-P
Application notes
ELISA: 1/100000.
IHC-P: 1/100. Perform heat mediated antigen retrieval via the pressure cooker method (with citrate buffer pH 6 or pH 8) before commencing with IHC staining protocol. See recommended protocol.
IHC-Fr: Use at an assay dependent dilution. Fix with ice cold acetone. See recommended protocol.
ICC (cytospun cells on slides): Use at an assay dependent dilution. Fix with ice cold acetone. See recommended protocol.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
The receptor for IL22 (also termed CRF29 and IL TIFR1 chain) is a member of the class II cytokine receptor family. IL22 Receptor forms a complex with IL10 Receptor beta chain and mediates IL22 signaling. IL22 and its receptor activate the JAK/STAT signaling pathway. IL22 Receptor is expressed in normal liver and kidney and their cell lines HepG2 and TK10.
Cellular localization
Cell Membrane
Alternative names
- CRF2 9 antibody
- cytokine receptor classII member 9 antibody
- cytokine receptor family 2 member 9 antibody
see all
Database links
- Entrez Gene: 58985 Human
- Omim: 605457 Human
- SwissProt: Q8N6P7 Human
- Unigene: 110915 Human
Anti-IL22 Receptor Alpha antibody images:
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) - IL22 Receptor antibody (ab18568)
ab18568 employed for the immunohistochemical detection of human N-terminal IL22 receptor, in paraffin embedded human spleen.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - IL22 Receptor Alpha antibody (ab18568)
ab18568 employed for the immunohistochemical detection of human N-terminal IL22 receptor, in paraffin embedded human tonsil.
References for Anti-IL22 Receptor Alpha antibody (ab18568)
ab18568 has not yet been referenced specifically in any publications.
Publishing research using ab18568? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"