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- Proteins and Peptides
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Product name
Anti-IL22 Receptor Alpha antibody
See all IL22 Receptor Alpha products (4) ...
Description
Rabbit polyclonal to IL22 Receptor Alpha
Tested applications
ICC/IF, WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse
Immunogen
Synthetic peptide: QSSNFENILTWDSGPE, corresponding to amino acids 31-46 of Human IL-22 Receptor.
QSSNFENILTWDSGPE
Positive control
HepG2 whole cell lysate.
General notes
Stable for one year.
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Adapters >> Transmembrane
Immunology >> Innate Immunity >> Cytokines >> Interleukins
Immunology >> Innate Immunity >> Macrophage / Inflamm.
Applications
Show applications key
Our Abpromise guarantee covers the use of ab5984 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
ICC/IF: Use at a concentration of 10 µg/ml.
IHC-P: Use at an assay dependent dilution (PMID 19535621).
WB: Use at a concentration of 0.5 - 1.0 µg/ml. Detects a band of approximately 62 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
The receptor for IL22 (also termed CRF29 and IL TIFR1 chain) is a member of the class II cytokine receptor family. IL22 Receptor forms a complex with IL10 Receptor beta chain and mediates IL22 signaling. IL22 and its receptor activate the JAK/STAT signaling pathway. IL22 Receptor is expressed in normal liver and kidney and their cell lines HepG2 and TK10.
Cellular localization
Cell Membrane
Alternative names
- CRF2 9 antibody
- cytokine receptor classII member 9 antibody
- cytokine receptor family 2 member 9 antibody
see all
Database links
- Entrez Gene: 58985 Human
- Entrez Gene: 230828 Mouse
- Omim: 605457 Human
- SwissProt: Q8N6P7 Human
- SwissProt: Q80XZ4 Mouse
- Unigene: 110915 Human
Anti-IL22 Receptor Alpha antibody images:
Western blot - IL22 Receptor Alpha antibody (ab5984)
Western blot analysis of IL-22R expression in human HepG2 cell lysate with ab5984 at 1µg /ml.
Immunocytochemistry/ Immunofluorescence - IL22 Receptor Alpha antibody (ab5984)
Immunocytochemistry of IL-22R in HepG2 cells with IL-22R antibody at 10 µg/ml.
References for Anti-IL22 Receptor Alpha antibody (ab5984)
This product has been referenced in:
- Andoh A et al. Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhanced in inflammatory bowel disease. J Immunol 183:687-95 (2009). IHC-P; Human.Read more (PubMed: 19535621) »
See 1 publication for this product
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"