![Western blot - IL3RB antibody [EP1037Y] (ab52609) image](#ab52609wb.jpg)
![Immunohistochemistry (Paraffin-embedded sections) - IL3RB antibody [EP1037Y] (ab52609) image](#ab52609ihc.jpg)
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Product name
Anti-IL3RB antibody [EP1037Y]
See all IL3RB products (7) ...
Description
Rabbit monoclonal [EP1037Y] to IL3RB
Tested applications
WB, IHC-Pmore details
Cross reactivity
Reacts with
Human
Does not react with
Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in the C-terminus of human IL3RB was used as an immunogen.
Positive control
TF1 cell lysate; Human lymphoma tissue.
General notes
Produced under U.S. Patent No. 5,675,063.
Properties
Form
Liquid
Storage instructions
Store at -20°C. Stable for 12 months at -20°C
Storage buffer
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purity
Tissue culture supernatant
Purification notes
Supplied as cell supernatant in storage buffer.
Clonality
Monoclonal
Clone number
EP1037Y
Isotype
IgG
Research areas
Applications
Show applications key
Our Abpromise guarantee covers the use of ab52609 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notes
IHC-P: 1/100 - 1/250. Antigen retrieval is strongly recommended.
WB: 1/5000. Predicted molecular weight: 130 kDa.
Is unsuitable for Flow Cyt, ICC or IP.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
Sequence similarities
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Contains 2 fibronectin type-III domains.
Domain
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation.
Cellular localization
Membrane.
Target information above from: UniProt accessionP32927
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- IL3RB antibody
- GM CSF/IL 3/IL 5 receptor common beta chain antibody
- GM CSF/IL 3/IL 5 receptor common beta-chain antibody
see all
Database links
- Entrez Gene: 1439 Human
- Omim: 138981 Human
- SwissProt: P32927 Human
- Unigene: 285401 Human
- Unigene: 592192 Human
Anti-IL3RB antibody [EP1037Y] images:
Western blot - IL3RB antibody [EP1037Y] (ab52609)
![Western blot - IL3RB antibody [EP1037Y] (ab52609)](/ps/datasheet/Images/52/ab52609/ab52609wb.jpg)
Anti-IL3RB antibody [EP1037Y] (ab52609) at 1/5000 dilution + TF1 cell lysate at 10 µg
Secondary
HRP-labelled goat anti-rabbit at 1/2000 dilution
Predicted band size : 130 kDa
Immunohistochemistry (Paraffin-embedded sections) - IL3RB antibody [EP1037Y] (ab52609)
![Immunohistochemistry (Paraffin-embedded sections) - IL3RB antibody [EP1037Y] (ab52609)](/ps/datasheet/Images/52/ab52609/ab52609ihc.jpg)
Immunohistochemical staining of paraffin-embedded human lymphoma using at a dilution of 1/100-1/250.
References for Anti-IL3RB antibody [EP1037Y] (ab52609)
This product has been referenced in:
- Medana IM et al. Erythropoietin and its receptors in the brainstem of adults with fatal falciparum malaria. Malar J 8:261 (2009). IHC-P; Human.Read more (PubMed: 19930602) »
See 1 publication for this product
Publishing research using ab52609? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"