Anti-IL8 antibody [B-K8] - Azide free (ab47198)

Overview

• Product nameAnti-IL8 antibody [B-K8] - Azide freeSee all IL8 primary antibodies ...
• Description
  Mouse monoclonal [B-K8] to IL8 - Azide free
• SpecificityThis antibody is specific for both natural and recombinant IL8.
• Tested applicationsFlow Cyt more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant full length IL8 protein (Human)

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: PBS
  Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free.
• Concentration information loading...
• PurityIon Exchange Chromatography
• Clonality Monoclonal
• Clone numberB-K8
• Myelomax63-Ag8.653
• IsotypeIgG1
• Research Areas
  • Cancer
  • Invasion/microenvironment
  • Angiogenesis
  • Angiogenic growth factors

  • Cardiovascular
  • Angiogenesis
  • Cytokines
  • Interleukin

  • Immunology
  • Innate Immunity
  • Cytokines
  • Interleukins

Applications

Target

• FunctionIL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
• Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
• Post-translational
  modificationsSeveral N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8. IL-8(6-77) is the most promiment form.
• Cellular localizationSecreted.

Target information above from: UniProt accession P10145 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 3576 Human
  • Omim: 146930 Human
  • SwissProt: P10145 Human
  • Unigene: 624 Human

• Alternative names
  (Ala-IL-8)77 antibody(Ser-IL-8)72 antibodyBbeta thromboglobulin like protein antibody

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