Anti-IL8 antibody [B-K8] (Phycoerythrin) (ab27369)
Overview
- Product nameAnti-IL8 antibody [B-K8] (Phycoerythrin)See all IL8 primary antibodies ...
- DescriptionMouse monoclonal [B-K8] to IL8 (Phycoerythrin)
- ConjugationPhycoerythrin
- SpecificityRecognises both natural and recombinant IL8.
- Tested applicationsFlow Cyt more details
- Species reactivityReacts with: Human
- Immunogen
Recombinant full length IL8 (Human)
Properties
- FormLyophilised:Reconstitute with 1 ml deionized water
- Storage instructionsStore at +4°C. Do not freeze.
- Storage bufferPreservative: 0.1% Sodium Azide
Constituents: 5% BSA, PBS -
Concentration information loading... - PurityIon Exchange Chromatography
- Clonality Monoclonal
- Clone numberB-K8
- Myelomax63-Ag8.653
- IsotypeIgG1
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab27369 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| Flow Cyt | Flow Cyt: Use at an assay dependent dilution. Use 10µl for 5 x 105 cells. (intra-cytoplasmic) |
Target
- FunctionIL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
- Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
- Post-translational
modificationsSeveral N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8. IL-8(6-77) is the most promiment form. - Cellular localizationSecreted.
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Database links
- Entrez Gene: 3576 Human
- Omim: 146930 Human
- SwissProt: P10145 Human
- Unigene: 624 Human
Target information above from: UniProt accession
P10145
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- (Ala-IL-8)77 antibody(Ser-IL-8)72 antibody3 10C antibody
- 310C antibodyAMCF 1 antibodyAMCF1 antibodyAMCF1 antibodyb ENAP antibodyBbeta thromboglobulin like protein antibodyBeta thromboglobulin like protein antibodyBeta thromboglobulin like protein antibodyC-X-C motif chemokine 8 antibodyCXC chemokine ligand 8 antibodyCXC chemokine ligand 8 antibodyCXCL 8 antibodyCXCL8 antibodyCXCL8 antibodyEmoctakin antibodyEmoctakin antibodyGCP 1 antibodyGCP-1 antibodyGCP/IL-8 protein I antibodyGCP/IL-8 protein II antibodyGCP/IL-8 protein III antibodyGCP/IL-8 protein IV antibodyGCP/IL-8 protein V antibodyGCP/IL-8 protein VI antibodyGCP1 antibodyGranulocyte chemotactic protein 1 antibodyIL 8 antibodyIL-8 antibodyIL-8(1-77) antibodyIL-8(9-77) antibodyIL8 antibodyIL8/NAP1 form I antibodyIL8/NAP1 form II antibodyIL8/NAP1 form III antibodyIL8/NAP1 form IV antibodyIL8/NAP1 form V antibodyIL8/NAP1 form VI antibodyIL8_HUMAN antibodyInteleukin 8 antibodyInteleukin 8 antibodyInterleukin8 antibodyK 60 antibodyK60 antibodyK60 antibodyLECT antibodyLECT antibodyLUCT antibodyLUCT antibodyLymphocyte derived neutrophil activating factor antibodyLymphocyte derived neutrophil activating factor antibodyLymphocyte-derived neutrophil-activating factor antibodyLYNAP antibodyLYNAP antibodyMDNCF antibodyMDNCF-b antibodyMDNCF-c antibodyMONAP antibodyMonocyte derived neutrophil activating peptide antibodyMonocyte derived neutrophil activating protein antibodyMonocyte derived neutrophil activating protein antibodyMonocyte derived neutrophil chemotactic factor antibodyMonocyte derived neutrophil chemotactic factor antibodyMonocyte-derived neutrophil chemotactic factor antibodyMonocyte-derived neutrophil-activating peptide antibodyNAF antibodyNAP 1 antibodyNAP-1 antibodyNAP1 antibodyNeutrophil activating factor antibodyNeutrophil activating factor antibodyNeutrophil activating peptide 1 antibodyNeutrophil activating peptide 1 antibodyNeutrophil activating protein 1 antibodyNeutrophil activating protein 1 antibodyNeutrophil-activating factor antibodyNeutrophil-activating protein 1 antibodyProtein 3 10C antibodyProtein 3-10C antibodySCYB 8 antibodySCYB8 antibodySCYB8 antibodySmall inducible cytokine subfamily B member 8 antibodyT cell chemotactic factor antibodyT cell chemotactic factor antibodyT-cell chemotactic factor antibodyTSG 1 antibodyTSG1 antibody
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References for Anti-IL8 antibody [B-K8] (Phycoerythrin) (ab27369)
ab27369 has not yet been referenced specifically in any publications.