Anti-IL8 antibody (ab106350)

Overview

• Product nameAnti-IL8 antibodySee all IL8 primary antibodies ...
• Description
  Rabbit polyclonal to IL8
• Tested applicationsWB, IHC-P more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide: CLDPKENWVQRVVEKFLKR, corresponding to C terminal amino acids 77-95 of Human IL8.

  Run BLAST with Run BLAST with
• Positive controlHuman appedicitis tissue. Recombinant Human IL8 protein

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.02% Sodium Azide, 0.01% Thimerosal (merthiolate)
  Constituents: 5mg BSA, 0.9mg Sodium chloride, 0.2mg Dibasic monohydrogen sodium phosphate
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Cancer
  • Invasion/microenvironment
  • Angiogenesis
  • Angiogenic growth factors

  • Cardiovascular
  • Angiogenesis
  • Cytokines
  • Interleukin

  • Immunology
  • Innate Immunity
  • Cytokines
  • Interleukins

Applications

Target

• FunctionIL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
• Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
• Post-translational
  modificationsSeveral N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8. IL-8(6-77) is the most promiment form.
• Cellular localizationSecreted.

Target information above from: UniProt accession P10145 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 3576 Human
  • Omim: 146930 Human
  • SwissProt: P10145 Human
  • Unigene: 624 Human

• Alternative names
  (Ala-IL-8)77 antibody(Ser-IL-8)72 antibodyBbeta thromboglobulin like protein antibody

  C-X-C motif chemokine 8 antibodyCXCL8 antibodyEmoctakin antibodyGCP-1 antibodyGCP/IL-8 protein I antibodyGCP/IL-8 protein II antibodyGCP/IL-8 protein III antibodyGCP/IL-8 protein IV antibodyGCP/IL-8 protein V antibodyGCP/IL-8 protein VI antibodyGCP1 antibodyGranulocyte chemotactic protein 1 antibodyIL-8 antibodyIL-8(1-77) antibodyIL-8(9-77) antibodyIL8 antibodyIL8/NAP1 form I antibodyIL8/NAP1 form II antibodyIL8/NAP1 form III antibodyIL8/NAP1 form IV antibodyIL8/NAP1 form V antibodyIL8/NAP1 form VI antibodyIL8_HUMAN antibodyInteleukin 8 antibodyLECT antibodyLUCT antibodyLymphocyte-derived neutrophil-activating factor antibodyLYNAP antibodyMDNCF antibodyMDNCF-b antibodyMDNCF-c antibodyMONAP antibodyMonocyte-derived neutrophil chemotactic factor antibodyMonocyte-derived neutrophil-activating peptide antibodyNAF antibodyNAP-1 antibodyNAP1 antibodyNeutrophil activating peptide 1 antibodyNeutrophil activating protein 1 antibodyNeutrophil-activating factor antibodyNeutrophil-activating protein 1 antibodyProtein 3 10C antibodyProtein 3-10C antibodySCYB8 antibodySmall inducible cytokine subfamily B member 8 antibodyT cell chemotactic factor antibodyT-cell chemotactic factor antibodyTSG1 antibody

  see all

Anti-IL8 antibody images

• 

  Western blot - IL8 antibody (ab106350)
  All lanes : Anti-IL8 antibody (ab106350) at 1 µg/ml
  
  Lane 1 : Recombinant Human IL8 protein at 20ng
  Lane 2 : Recombinant Human IL8 protein at 10ng
  Lane 3 : Recombinant Human IL8 protein at 5ng
  Lane 4 : Raji whole cell lysate
  Lane 5 : MK (55kD)
  
  
  Predicted band size : 11 kDa
  
• 

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - IL8 antibody (ab106350)
  ab106350, at 1µg/ml, staining IL8 in paraffin-embedded Human appedicitis tissue by Immunohistochemistry.