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Overview

  • Product nameIMPA1 proteinSee all IMPA1 proteins and peptides ...
  • Protein descriptionRecombinant full length Human IMPA1 (amino acids 1-277) with N terminal His tag; 297 amino acids with tag, MWt 32.3 kDa (UniProt P29218).
  • Uniprot accessionP29218
  • Molecular weight32.300kDa inclusive of tags
  • Protein length277 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab99519 was purified using conventional chromatography.
  • Mass spectrometryMALDI-TOF
  • E.C. Number3.1.3.25
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0
  • Concentration information loading...
  • SequenceMGSSHHHHHHSSGLVPRGSHMADPWQECMDYAVTLARQAG EVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVH RFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAF CNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME KLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWD VAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAE RIAKEIQVIPLQRDDED
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab99519 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    MS MS: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab154372 and ab169324.

    • Protein info

    • Alternative names
        IMPIMP 1IMPA
        IMPA 1IMPA1IMPA1_HUMANIMPaseIMPase 1Inositol 1(or 4) monophosphataseInositol monophosphataseInositol monophosphatase 1Inositol(myo) 1(or 4) monophosphatase 1Inositol-1(or 4)-monophosphatase 1Lithium sensitive myo inositol monophosphatase A1Lithium-sensitive myo-inositol monophosphatase A1
      see all
  • FunctionResponsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Can use myo-inositol monophosphates, myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.
  • PathwayPolyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.
  • Sequence similaritiesBelongs to the inositol monophosphatase family.
  • Cellular localizationCytoplasm.

    • Target information above from: UniProt accession P29218 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    IMPA1 protein images

    • SDS-PAGE - IMPA1 protein (ab99519)
      SDS-PAGE - IMPA1 protein (ab99519)
      15% SDS-PAGE analysis of 3µg ab99519.

    References for IMPA1 protein (ab99519)

    ab99519 has not yet been referenced specifically in any publications.

    Publishing research using ab99519 ? Please let us know so that we can cite the reference in this datasheet

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