Recombinant
RabMAb

Anti-ING1 antibody [EPR6788] (ab124893)

Overview

  • Product name
    Anti-ING1 antibody [EPR6788]
    See all ING1 primary antibodies
  • Description
    Rabbit monoclonal [EPR6788] to ING1
  • Tested applications
    Suitable for: WB, Flow Cytmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human ING1. (Uniprot: Q9UK53)

  • Positive control
    • HepG2 lysate, HeLa lysate, MCF-7 lysate, Jurkat lysate, C6 lysate, RAW264.7 lysate, PC-12 lysate and NIH/3T3 lysate.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab124893 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 47 kDa.
Flow Cyt 1/10 - 1/100. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function
      Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene.
    • Tissue specificity
      Isoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines.
    • Involvement in disease
      Defects in ING1 are a cause of head and neck squamous cell carcinomas (HNSCC) [MIM:275355]; also known as squamous cell carcinoma of the head and neck.
    • Sequence similarities
      Belongs to the ING family.
      Contains 1 PHD-type zinc finger.
    • Cellular localization
      Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • 2610028J21Rik antibody
      • AA407184 antibody
      • AI875420 antibody
      • Growth inhibitor ING 1 antibody
      • Growth inhibitor ING1 antibody
      • Growth inhibitory protein ING 1 antibody
      • Growth inhibitory protein ING1 antibody
      • Homo sapiens growth inhibitor p33ING1 (ING1) mRNA, complete cds antibody
      • ING 1 antibody
      • Ing1 antibody
      • ING1_HUMAN antibody
      • Inhibitor of growth 1 antibody
      • Inhibitor of growth family member 1 antibody
      • Inhibitor of growth protein 1 antibody
      • mING1h antibody
      • OTTHUMP00000018703 antibody
      • OTTHUMP00000018704 antibody
      • OTTHUMP00000018705 antibody
      • OTTHUMP00000018706 antibody
      • p24ING1c antibody
      • p33 antibody
      • p33 ING1 antibody
      • p33ING1 antibody
      • p33ING1b antibody
      • p33ING1c antibody
      • p37Ing1b antibody
      • p47 antibody
      • p47ING1a antibody
      • Tumor suppressor ING 1 antibody
      • Tumor suppressor ING1 antibody
      see all

    Images

    • All lanes : Anti-ING1 antibody [EPR6788] (ab124893) at 1/1000 dilution

      Lane 1 : HepG2 lysate
      Lane 2 : HeLa lysate
      Lane 3 : MCF-7 lysate
      Lane 4 : Jurkat lysate
      Lane 5 : C6 lysate
      Lane 6 : RAW 264.7 lysate
      Lane 7 : PC-12 lysate
      Lane 8 : NIH/3T3 lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 47 kDa
    • Flow Cytometric analysis of ab124893, at 1/10 dilution, staining ING1 in permeabilised NIH/3T3cells (red). Isotype control (Green).

    References

    ab124893 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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