Anti-ING1 antibody (ab55306)

Overview

• Product nameAnti-ING1 antibodySee all ING1 primary antibodies ...
• Description
  Mouse monoclonal to ING1
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant fragment, corresponding to amino acids 41-141 of Human ING1

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: Ascites
• Concentration information loading...
• PurityAscites
• Clonality Monoclonal
• IsotypeIgM
• Light chain typekappa
• Research Areas
  • Cancer
  • Oncoproteins/suppressors
  • Tumor suppressors
  • p53 pathway

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Cancer susceptibility
  • Tumor Suppressors

  • Epigenetics and Nuclear Signaling
  • Chromatin Modifying Enzymes
  • Acetylation
  • HAT

  • Cell Biology
  • Apoptosis
  • Intracellular
  • p53 Pathway

Applications

Target

• FunctionCooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene.
• Tissue specificityIsoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines.
• Involvement in diseaseDefects in ING1 are a cause of head and neck squamous cell carcinomas (HNSCC) [MIM:275355]; also known as squamous cell carcinoma of the head and neck.
• Sequence similaritiesBelongs to the ING family.
  Contains 1 PHD-type zinc finger.
• Cellular localizationNucleus.

Target information above from: UniProt accession Q9UK53 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 3621 Human
  • GenBank: NP_937862 Human
  • Omim: 601566 Human
  • SwissProt: Q9UK53 Human
  • Unigene: 46700 Human
  • Unigene: 508725 Human

• Alternative names
  2610028J21Rik antibodyAA407184 antibodyAI875420 antibody

  Growth inhibitor ING 1 antibodyGrowth inhibitor ING1 antibodyGrowth inhibitory protein ING 1 antibodyGrowth inhibitory protein ING1 antibodyHomo sapiens growth inhibitor p33ING1 (ING1) mRNA, complete cds antibodyING 1 antibodyIng1 antibodyING1_HUMAN antibodyInhibitor of growth 1 antibodyInhibitor of growth family member 1 antibodyInhibitor of growth protein 1 antibodymING1h antibodyOTTHUMP00000018703 antibodyOTTHUMP00000018704 antibodyOTTHUMP00000018705 antibodyOTTHUMP00000018706 antibodyp24ING1c antibodyp33 antibodyp33 ING1 antibodyp33ING1 antibodyp33ING1b antibodyp33ING1c antibodyp37Ing1b antibodyp47 antibodyp47ING1a antibodyTumor suppressor ING 1 antibodyTumor suppressor ING1 antibody

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Anti-ING1 antibody images

• 

  Western blot - ING1 antibody (ab55306)
  
  
  Predicted band size : 47 kDa
  ING1 antibody (ab55306) at 1ug/lane + HeLa cell lysate at 25ug/lane.