Anti-ING1 antibody (ab55306)
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
- Concentration information loading...
- Clonality Monoclonal
- Light chain typekappa
Our Abpromise guarantee covers the use of ab55306 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- FunctionCooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene.
- Tissue specificityIsoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines.
- Involvement in diseaseDefects in ING1 are a cause of head and neck squamous cell carcinomas (HNSCC) [MIM:275355]; also known as squamous cell carcinoma of the head and neck.
- Sequence similaritiesBelongs to the ING family.
Contains 1 PHD-type zinc finger.
- Cellular localizationNucleus.
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Anti-ING1 antibody images
Predicted band size : 47 kDa
ING1 antibody (ab55306) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-ING1 antibody (ab55306)
ab55306 has not yet been referenced specifically in any publications.