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Anti-ING3 antibody (ab57388)

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Overview

Product name

Anti-ING3 antibody
See all ING3 products (6) ...

Description

Mouse monoclonal to ING3

Tested applications

WBmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Recombinant fragment: MLYLEDYLEM IEQLPMDLRD RFTEMREMDL QVQNAMDQLE QRVSEFFMNA KKNKPEWREE QMASIKKDYY KALEDADEKV QLANQIYDLQ HF, corresponding to amino acids 1-93 of Human ING3

MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLE QRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADEKV QLANQIYDLQHF

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Isotype

IgG2b

Light chain type

kappa

Research areas

Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation >> HAT
Epigenetics and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Tumor Suppressors
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation

  • Western blot - ING3 antibody (ab57388)Western blot - ING3 antibody (ab57388) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab57388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

WB: Use at a concentration of 1-5 µg/ml.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

ING3 belongs to a family of proteins containing the plant homeodomain (PHD) finger, which includes transcription factors and proteins that regulate chromatin structure. ING3 is a component of the NuA4 histone acetyltransferase (HAT) complex and can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of ING3 has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of the ING3 gene were detected in head and neck cancers.

Cellular localization

Nuclear

Alternative names

  • 1300013A07Rik antibody
  • Eaf 4 antibody
  • Eaf4 antibody
  • FLJ20089 antibody
  • ING 2 antibody
  • ING 3 antibody
  • ING2 antibody
  • Inhibitor of growth family member 3 antibody
  • Inhibitor of growth protein 3 antibody
  • p47 ING 3 antibody
  • p47 ING3 antibody
  • p47 regulator protein antibody
  • p47ING3 antibody
  • p47ING3 protein antibody
see all

Database links

Anti-ING3 antibody images:

  Western blot - ING3 antibody (ab57388)

Western blot - ING3 antibody (ab57388)

ING3 antibody (ab57388) at 1ug/lane + PC-12 cell lysate at 25ug/lane.

References for Anti-ING3 antibody (ab57388)

This product has been referenced in:

See 1 publication for this product

Publishing research using ab57388? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"