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Overview

  • Product nameAnti-INTS2 antibody
  • Description
    Rabbit polyclonal to INTS2
  • Tested applicationsWB, ELISA more details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    synthesized peptide derived from an internal sequence of human INTS2

  • Positive controlextracts from RAW264.7 cells

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% None
    Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Clonality Polyclonal
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab74982 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: 1/500 - 1/1000. Predicted molecular weight: 134 kDa.
ELISA ELISA: 1/20000.

Target

  • Relevance INTS2 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]). INTS2 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
  • Cellular localizationNuclear membrane
  • Database links
    • Alternative names
        INT2 antibodyIntegrator complex subunit 2 antibody

    Anti-INTS2 antibody images

    • Western blot - INTS2 antibody (ab74982)
      Western blot - INTS2 antibody (ab74982)
      All lanes : Anti-INTS2 antibody (ab74982) at 1/500 dilution

      Lane 1 : extracts from RAW264.7 cells
      Lane 2 : extracts from RAW264.7 cells with immunizing peptide at 5 µg

      Lysates/proteins at 15 µg per lane.


      Predicted band size : 134 kDa
      Observed band size : 140 kDa (why is the actual band size different from the predicted?)

    References for Anti-INTS2 antibody (ab74982)

    ab74982 has not yet been referenced specifically in any publications.

    Publishing research using ab74982 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"