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Overview

  • Product nameIP10 protein (Active)See all IP10 proteins and peptides ...
  • Protein descriptionRecombinant fragment, corresponding to amino acids 23-104 of Pig IP10, expressed in Yeast, Predicted MWt 9.3 kDa (Swiss-Prot Q2EN90).
  • Expression hostYeast

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab87388 is purified using Ion-exchange chromatography.
  • Biological activityThe biological activity of recombinant swine IP10 was determined in a chemotaxis assay using a Boyden chamber. Swine PBMCs were activated with PHA for 3 days followed by treatment with IL-2. Bioactivity is typically detected at 10 ng/mL.
  • FormLyophilised:Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
  • Storage instructionsStore at -20°C. Stable for 12 months at -20°CThis product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Storage bufferPreservative: None
    Constituents: 10% Trehalose, 1.0X PBS
  • Concentration information loading...
  • Sequence notesPLSRTVRCTC IKISDRPVNP RSLEKLEMIP ASQSCPHVEI IATMKKNGEK RCLNPESKTI KNLLKAISKE RSKRSPRTQR EA
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab87388 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
    Cellular activation CellAct: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        10 kDa interferon gamma induced protein10 kDa interferon gamma-induced proteinC X C motif chemokine 10
        C7Chemokine (C X C motif) ligand 10Chemokine CXC motif ligand 10Crg 2CRG2CXCL10CXCL10(1-73)CXL10_HUMANGamma IP10Gamma-IP10gIP 10GIP10IFI10INP 10INP10Interferon activated gene 10Interferon gamma induced cell lineInterferon inducible cytokine IP 10Interferon inducible cytokine IP10IP 10IP-10Mob 1MOB1Protein 10 from interferon (gamma) induced cell lineSCYB10Small inducible cytokine B10Small inducible cytokine B10 precursorSmall inducible cytokine subfamily B (Cys X Cys) member 10Small inducible cytokine subfamily B CXC member 10Small-inducible cytokine B10
      see all
  • FunctionChemotactic for monocytes and T-lymphocytes. Binds to CXCR3.
  • Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications    CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession P02778 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for IP10 protein (Active) (ab87388)

    ab87388 has not yet been referenced specifically in any publications.

    Publishing research using ab87388 ? Please let us know so that we can cite the reference in this datasheet

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