You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Anti-IRAK2 antibody (ab25957)

CodeSizePriceAbpointsAvailability
    
Add to basket
 

  • -

  •   
  •   
  •   

  •  

  •  
  •  

  •  

  •  
Updating...

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »

Overview

Product name

Anti-IRAK2 antibody
See all IRAK2 products (8) ...

Description

Rabbit polyclonal to IRAK2

Specificity

ab25957 recognises IRAK2 but does not cross-react with IRAK.

Tested applications

WBmore details

Cross reactivity

Reacts with

Mouse

Immunogen

Synthetic peptide, corresponding to 16 C terminal amino acids of Mouse IRAK2a isoform. This sequence is common to all four isoforms.

Positive control

Whole cell lysate from A-20 cells.

Properties

Form

Liquid

Storage instructions

Store at +4°C.

Storage buffer

Preservative: 0.02% Sodium Azide
Constituents: PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Immunology >> Innate Immunity >> TLR Signaling
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> Other Kinases
Immunology >> Innate Immunity >> Cytokines >> Interleukins

  • Western blot - IRAK2 antibody (ab25957)Western blot - IRAK2 antibody (ab25957) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab25957 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

Tissue specificity

Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.

Sequence similarities

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
Contains 1 death domain.
Contains 1 protein kinase domain.

Domain

The protein kinase domain is predicted to be catalytically inactive.

Target information above from: UniProt accessionO43187 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Interleukin 1 receptor associated kinase like 2 antibody
  • il1rak2 antibody
  • Interleukin 1 receptor associated kinase 2 antibody
  • Interleukin 1 receptor associated kinase 2 antibody
  • Interleukin 1 receptor-associated kinase like 2 antibody
  • Interleukin-1 receptor-associated kinase-like 2 antibody
  • IRAK 2 antibody
  • IRAK 2 antibody
  • IRAK-2 antibody
  • IRAK2 antibody
  • IRAK2 antibody
  • IRAK2_HUMAN antibody
  • MGC150550 antibody
see all

Database links

Anti-IRAK2 antibody images:

  Western blot - IRAK2 antibody (ab25957)

Western blot - IRAK2 antibody (ab25957)

Lane 1 : Anti-IRAK2 antibody (ab25957) at 0.5 µg/ml
Lane 2 : Anti-IRAK2 antibody (ab25957) at 1 µg/ml
Lane 3 : Anti-IRAK2 antibody (ab25957) at 2 µg/ml

Lane 1 : A-20 whole cell lysate
Lane 2 : A-20 whole cell lysate
Lane 3 : A-20 whole cell lysate


Predicted band size : 65 kDa

References for Anti-IRAK2 antibody (ab25957)

ab25957 has not yet been referenced specifically in any publications.

Publishing research using ab25957? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"