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Overview

  • Product nameIgG2 protein (Human)See all IgG2 proteins and peptides ...
  • Protein descriptionFull length native Human IgG2 purified from Human Myeloma Plasma, 146kDa.
  • Expression hostNative

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Biological activityShown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 and 2 by FDA approved tests.
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.05% Sodium Azide
    Constituents: 20mM PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • Additional notesProtein Determination: Extinction Coefficient (E) 0.1% at 280nm =1.36.
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab90284 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        DKFZp686I04196G2m markerIg gamma 2 chain C region
        IGHG 2IGHG2Immunoglobulin heavy constant gamma 2
      see all
  • RelevanceThere are four IgG subclasses (IgG1, 2, 3 and 4) in humans, named in order of their abundance in serum (IgG1 being the most abundant). IgG2 is the only IgG subclass which passes through the placenta at a level generally lower than that found in the mother. A deficiency of IgG2 indicates a poor antibody response to bacterial polysaccharides and can lead to increased susceptibility to infections caused by encapsulated bacteria.
  • Cellular localizationSecreted

    • References for IgG2 protein (Human) (ab90284)

    ab90284 has not yet been referenced specifically in any publications.

    Publishing research using ab90284 ? Please let us know so that we can cite the reference in this datasheet

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    I have some questions about these products:

    IgG1 protein (ab90283)
    IgG2 protein (ab90284)
    IgG3 protein (ab118426)
    IgG4 protein (ab90286)

    In what volumes and in what concentrations do they come?

    I really appr...

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    Thank you for your email.

    I am happy to check these concentrations for you. Please find here below the answers:

    IgG1 protein (ab90283) you will receive 1 mg at 3.41mg/ml, ¨so it will be in 293ul



    IgG2 protein (a...

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    What is the sequence for this IgG2 protein?

    Thank you for contacting us. Because this IgG2 was purified from human myeloma plasma, we do not know the exact sequence. The sequence of the C region of human IgG2 can be found on the UniProt database: http://www.uniprot.org/uniprot/P01859 ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"