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Overview

  • Product nameIgG3 protein (Human)See all IgG3 proteins and peptides ...
  • Protein descriptionHuman IgG3 prepared from Human plasma.
  • Uniprot accessionP01860
  • Molecular weight170kDa
  • Expression hostNative

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab118426 is prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
  • FormLiquid
  • Storage instructionsStore at +4°C. Do not freeze.
  • Storage bufferpH: 7.40
    Preservative: 0.05% Sodium azide
    Constituents: 0.32% Sodium phosphate, 0.88% Sodium chloride
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab118426 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.

    Protein info

    • Alternative names
        DKFZp686H11213FLJ39988FLJ40036
        FLJ40253FLJ40587FLJ40789FLJ40834HDCHeavy chain disease proteinIg gamma 3 chain C regionIGHG3Immunoglobulin heavy constant gamma 3 (G3m marker)MGC45809
      see all
  • RelevanceIgG3, like IgG1, activates complement and has an affinity for fc receptors; thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection.
  • Cellular localizationSecreted

    • References for IgG3 protein (Human) (ab118426)

    ab118426 has not yet been referenced specifically in any publications.

    Publishing research using ab118426 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab118426 Submit a Question for ab118426

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    Is there any information on the cross reactivity of ab118426 with IgA, D E and M?

    Thank you once again for your recent enquiries.

    I have now received information to confirm that ab118426 is purified from normal plasma, and shows no reaction to antisera to human IgA, IgD, IgE or IgM.

    I hope this information is help...

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    I have some questions about these products:

    IgG1 protein (ab90283)
    IgG2 protein (ab90284)
    IgG3 protein (ab118426)
    IgG4 protein (ab90286)

    In what volumes and in what concentrations do they come?

    I really appr...

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    Thank you for your email.

    I am happy to check these concentrations for you. Please find here below the answers:

    IgG1 protein (ab90283) you will receive 1 mg at 3.41mg/ml, ¨so it will be in 293ul



    IgG2 protein (a...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"