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Anti-Influenza A Virus M1 antibody [GA2B] (ab22396)

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Overview

Product name

Anti-Influenza A Virus M1 antibody [GA2B]
See all Influenza A Virus M1 products (4) ...

Description

Mouse monoclonal [GA2B] to Influenza A Virus M1

Tested applications

Flow Cyt, IHC-P, WB, ICC/IFmore details

Cross reactivity

Reacts with Influenza A. Not yet tested in other species.

Immunogen

Tissue / cell preparation- Influenza A / Puerto Rico / 8 / 34 (H1N1) and A/Bangkok / 1 / 79 (H3N2) viruses

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

pH: 7.50
Preservative: 0.09% Sodium azide
Constituent: PBS

Concentration

Concentration information loading...

Purity

Protein A purified

Clonality

Monoclonal

Clone number

GA2B

Myeloma

P3x63-Ag8.653

Isotype

IgG1

Research areas

Microbiology >> Organism >> Virus >> RNA Virus >> single stranded RNA negative strand virus >> Influenza

  • Flow Cytometry - Anti-Influenza A Virus M1 antibody [GA2B] (ab22396)Flow Cytometry - Anti-Influenza A Virus M1 antibody [GA2B] (ab22396) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab22396 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Influenza virus type A matrix protein, also known as M1, is composed of a 252 amino acid sequence and is type-specific in influenza viruses. It is located inside the viral lipid envelope and plays a key role in virus assembly and replication. M1 can be isolated from particles by removing the envelope with detergents and reducing the pH to 4.0. Influenza viruses are a common and widely spread infectious agent. Like many other viruses, influenza virus are constantly undergoing mutations and thereby avoiding the immune system. The Influenza A Virus M proteins form a continuous shell on the inner side of the lipid bilayer, maintaining the structural integrity of the virus particle through hydrophobic interactions.

Cellular localization

Cytoplasmic

Alternative names

  • FLUAVAHHH9N2s7gp2 antibody
  • FLUAVs7gp1 antibody
  • M1 antibody
  • M1 matrix protein 1 antibody
  • Matrix Protein 1 antibody
  • Matrix Protein I antibody
  • Membrane matrix protein M1 antibody
see all

Anti-Influenza A Virus M1 antibody [GA2B] images:

  Flow Cytometry - Anti-Influenza A Virus M1 antibody [GA2B] (ab22396)

Flow Cytometry - Anti-Influenza A Virus M1 antibody [GA2B] (ab22396)

ab22396 used in Flow Cytometry.

Influenza infected A549 cells were trypsinized, fixed in paraformaldehyde, permeabilized and then incubated with ab22396 for analysis by Flow Cytometry.

ab22396 used at a 1/200 dilution.
The secondary used was ab96874, diluted 1/200.

Image courtesy of an anonymous Abreview.

See Abreview

References for Anti-Influenza A Virus M1 antibody [GA2B] (ab22396)

This product has been referenced in:

  • Chase GPet al. Influenza Virus Ribonucleoprotein Complexes Gain Preferential Access to Cellular Export Machinery through Chromatin Targeting. PLoS Pathog 7:e1002187 (2011). WB, ICC/IF.Read more (PubMed: 21909257) »
  • Meuter Set al. Prolonged antigen survival and cytosolic export in cross-presenting human gammadelta T cells. Proc Natl Acad Sci U S A 107:8730-5 (2010). Flow Cyt.Read more (PubMed: 20413723) »

See all 3 publications for this product

Publishing research using ab22396? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"