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Products:Microbiology >> Organism >> Virus >> RNA Virus >> single stranded RNA negative strand virus >> Influenza
Overview
Product name
Anti-Influenza A Virus Nucleoprotein antibody [9G8]
See all Influenza A Virus Nucleoprotein products (10) ...
Description
Mouse monoclonal [9G8] to Influenza A Virus Nucleoprotein
Specificity
Recognizes Nucleoprotein of Influenza A virus group specific antigen (H0N1, H1N1, H2N2 and H3N2).
Tested applications
ELISA, WB, ICCmore details
Cross reactivity
Influenza A. No cross-reactivity with influenza B or with other respiratory viruses.
Immunogen
Recombinant nucleoprotein
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: Ascites
Concentration
Concentration information loading...
Purity
Ascites
Clonality
Monoclonal
Clone number
9G8
Isotype
IgG2a
Light chain type
kappa
Research areas
Microbiology >> Organism >> Virus >> RNA Virus >> single stranded RNA negative strand virus >> Influenza
Applications
Show applications key
Our Abpromise guarantee covers the use of ab43821 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
ELISA: 1/2000 - 1/10000.ELISA: 1/2000 - 1/10000.
WB
WB: 1/200 - 1/1000.WB: 1/200 - 1/1000.
ICC: 1/100 - 1/500.(On infected cells.)
Target
Relevance
The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002).
Cellular localization
Host cell nucleus
Alternative names
- Common flu NP antibody
- Influenza A virus NP antibody
- Matrix protein M1 antibody
see all
References for Anti-Influenza A Virus Nucleoprotein antibody [9G8] (ab43821)
ab43821 has not yet been referenced specifically in any publications.
Publishing research using ab43821? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"