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Product Name 

Integrin alpha 2+beta 1 antibody [BMA2.1] - Azide free

 

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Product type 

Primary antibodies

Description 

Rat monoclonal [BMA2.1] to Integrin alpha 2+beta 1 - Azide free

Immunogen 

Mouse Integrin alpha 2+beta 1 heterodimer

Reacts with 
(species key)

Ms

Specificity 

Directed against Integrin alpha 2+beta 1 heterodimer. The antibody does not recognize the alpha 2 or beta 1 subunits individually.

Tested applications 
(see key)

BL, Flow Cyt, IP


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
BL of integrin alpha 2+beta 1 mediated adhesion: Use at an assay dependent dilution.
Flow Cyt: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.

Is unsuitable for IHC.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cell Membrane; single-pass type I membrane protein

Research areas 

Cancer >> Cancer Metabolism >> Response to hypoxia
Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> Integrins >> Beta
Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> Integrins >> Alpha

Relevance 

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumour cells.

 

Alternative names Integrin alpha 2+beta 1 antibody [BMA2.1] - Azide free (ab77991)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

16398    (Mouse)
16412    (Mouse)

SwissProt

    

Q62469    (Mouse)
P09055    (Mouse)

Raised in 

Rat

Clonality 

Monoclonal

Clone number 

BMA2.1

Isotype 

IgG1

Purity 

Protein A purified

Storage buffer 

Preservative: None

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Store at +4°C.

 

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