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Product Name
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Integrin alpha 2+beta 1 antibody [BMA2.1] - Azide free
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See all Integrin alpha 2+beta 1 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Rat monoclonal [BMA2.1] to Integrin alpha 2+beta 1 - Azide free
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Immunogen
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Mouse Integrin alpha 2+beta 1 heterodimer
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Reacts with
(species key)
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Ms
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Specificity
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Directed against Integrin alpha 2+beta 1 heterodimer. The antibody does not recognize the alpha 2 or beta 1 subunits individually.
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Tested applications
(see key)
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BL, Flow Cyt, IP
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Abreviews
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Application notes
(see key)
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Recommended dilutions BL of integrin alpha 2+beta 1 mediated adhesion: Use at an assay dependent dilution. Flow Cyt: Use at an assay dependent dilution. IP: Use at an assay dependent dilution.
Is unsuitable for IHC.
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cell Membrane; single-pass type I membrane protein
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Research areas
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Cancer >> Cancer Metabolism >> Response to hypoxia Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> Integrins >> Beta Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> Integrins >> Alpha
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Relevance
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Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumour cells.
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Database links
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The links below go to external sites and will open in a new browser window
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Raised in
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Rat
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Clonality
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Monoclonal
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Clone number
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BMA2.1
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Isotype
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IgG1
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Purity
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Protein A purified
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Storage buffer
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Preservative: None
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C.
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Search PubMed (MEDLINE) for references to Integrin alpha 2+beta 1
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