Integrin alpha 2+beta 1 antibody [k2D5] (ab72843)

Product Name 

Integrin alpha 2+beta 1 antibody [k2D5]

Product type 

Primary antibodies

Description 

Mouse monoclonal [k2D5] to Integrin alpha 2+beta 1

Immunogen 

Recombinant human Integrin alpha 2 beta 1 (34 - 141 aa) purified from E. coli

Reacts with 
(species key)

Hu

Tested applications 
(see key)

ELISA, WB

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
ELISA: Use at an assay dependent dilution.
WB: 1/500 - 1/1000. Detects a band of approximately 131 kDa (predicted molecular weight: 131 kDa).

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Cell lysates of U937

Cellular localization 

Cell Membrane; single-pass type I membrane protein

Research areas 

Cancer >> Cancer Metabolism >> Response to hypoxia
Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> Integrins >> Beta
Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> Integrins >> Alpha

Relevance 

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumour cells.

ab72843 is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Integrin alpha 2 beta 1 protein.

Database links 

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

k2D5

Isotype 

IgG1

Light chain type 

kappa

Purity 

Protein G purified

Storage buffer 

Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

ab72843 was purified from mouse ascitic fluids by protein G affinity chromatography.

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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