Ionotropic Glutamate receptor 2 antibody [EP966Y] (ab52932)

Product Name 

Ionotropic Glutamate receptor 2 antibody [EP966Y]

Product type 

Primary antibodies

Description 

Rabbit monoclonal [EP966Y] to Ionotropic Glutamate receptor 2

Immunogen 

Synthetic peptide corresponding to residues near the N terminus of human GluR2.

Reacts with 
(species key)

Hu, Ms, Rat

Tested applications 
(see key)

Flow Cyt, IP, WB

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
Flow Cyt: 1/30.
IP: 1/40.
WB: 1/2000. Detects a band of approximately 110 kDa (predicted molecular weight: 99 kDa).

Is unsuitable for ICC/IF or IHC.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Human brain cell lysate.

Cellular localization 

Cell Membrane

Research areas 

Neuroscience >> Neurotransmission >> Receptors / Channels >> GPCR >> Glutamate Receptors
Neuroscience >> Neurotransmitter >> Amino Acids >> Glutamate

Relevance 

Glutamate receptors sensitive to AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate) are ligand-activated cation channels that mediate the fast component of excitatory postsynaptic currents in neurons of the central nervous system. These channels are assembled from 4 related subunits, GLURA (GRIA1), GLURB (GRIA2), GLURC (GRIA3), GLURD (GRIA4), with the GLURB subunit rendering the channel almost impermeable to Ca(2+).

Database links 

Raised in 

Rabbit

Clonality 

Monoclonal

Clone number 

EP966Y

Isotype 

IgG

Purity 

Tissue culture supernatant

Storage buffer 

Preservative: 0.25% Sodium Azide
Constituents: 40% Glycerol, 0.5% BSA, 0.18M Sodium chloride, 50mM Tris glycine, 25mM Citric acid, 0.25mM EDTA, pH 7.4

Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Notes 

Produced under U.S. Patent No. 5,675,063.

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