Overview

  • Product name
    Isotetrandrine
  • Description
    Cell-permeable PLA2 inhibitor
  • Biological description
    Cytoplasmic phospholipase A2 (PLA2) inhibitor. Also shown to inhibit α1 adrenoceptor (Ki = 1.6 μM). Cell-permeable. Active in vivo.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Chan D  et al. Inhibition of membrane tubule formation and trafficking by isotetrandrine, an antagonist of G-protein-regulated phospholipase A2 enzymes. Mol Biol Cell 15:1871-80 (2004). Read more (PubMed: 14767064) »
  • Catret M  et al. Alpha-adrenoceptor interaction of tetrandrine and isotetrandrine in the rat: functional and binding assays. J Pharm Pharmacol 50:1267-73 (1998). Read more (PubMed: 9877313) »
  • Kondo Y  et al. Selective inhibition of T-cell-dependent immune responses by bisbenzylisoquinoline alkaloids in vivo. Int J Immunopharmacol 14:1181-6 (1992). Read more (PubMed: 1452403) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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