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Overview

  • Product nameJAKMIP1 protein (His-DHFR tag)See all JAKMIP1 proteins and peptides ...
  • Protein descriptionRecombinant fragment of Human JAKMIP1 (amino acids 282-436) with N terminal His-DHFR tag, 18.7 kDa (calculated without tag). (UniProt ID = Q96N16).
  • Uniprot accessionQ96N16
  • Molecular weight18.700kDa
  • Protein length155 amino acids
  • Expression hostE. coli

    • Properties

  • Purification notesPurity was determined to be >95% by SDS-PAGE.
  • FormLyophilised:Reconstitute with water to desired concentration.
  • Storage instructionsShipped at 4°C. Store at -20ºC.
  • Storage bufferConstituents: 0.32% Tris HCl, 0.58% Sodium chloride
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab127233 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        FLJ31564GABA B receptor binding proteinGABA-B receptor-binding protein
        GABABRBPJak and microtubule interacting protein 1JAKMIP 1JAKMIP1JAMIP1Janus kinase and microtubule interacting protein 1Janus kinase and microtubule-interacting protein 1JKIP1_HUMANMarlin 1Marlin-1MARLIN1Multiple alpha-helices and RNA-linker protein 1Multiple coiled coil GABABR1 binding proteinOTTHUMP00000155144OTTHUMP00000203209OTTHUMP00000203210OTTHUMP00000203212OTTHUMP00000217225OTTHUMP00000217781
      see all
  • FunctionAssociates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
  • Tissue specificityPredominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine.
  • Sequence similaritiesBelongs to the JAKMIP family.
  • Cellular localizationCytoplasm > cytoskeleton. Membrane. Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.

    • Target information above from: UniProt accession Q96N16 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for JAKMIP1 protein (His-DHFR tag) (ab127233)

    ab127233 has not yet been referenced specifically in any publications.

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