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Anti-JAML antibody (ab67843)

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Overview

Product name

Anti-JAML antibody
See all JAML products (2) ...

Description

Mouse polyclonal to JAML

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

JAML (AAI00798.1, 1 a.a. ~ 355 a.a) full-length human protein.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein A purified

Clonality

Polyclonal

Isotype

IgG

  • Western blot - JAML antibody (ab67843)Western blot - JAML antibody (ab67843) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab67843 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: 1/500 - 1/1000.Detec...Read more →

    WB: 1/500 - 1/1000.Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa).

Target

Function

May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.

Tissue specificity

Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.

Sequence similarities

Belongs to the immunoglobulin superfamily.
Contains 2 Ig-like V-type (immunoglobulin-like) domains.

Domain

The Ig-like V-type domain 2 mediates interaction with CXADR.

Cellular localization

Cell junction. Cell membrane. Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.

Target information above from: UniProt accessionQ86YT9 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • adhesion molecule AMICA antibody
  • Adhesion molecule interacting with CXADR antigen 1 antibody
  • adhesion molecule interacts with CXADR antigen 1 antibody
  • adhesion molecule that interacts with CXADR antigen 1 antibody
  • AMICA antibody
  • AMICA1 antibody
  • CREA7-1 antibody
  • CREA7-4 antibody
  • Dendritic cell-specific protein CREA7-1 antibody
  • dendritic-cell specific protein CREA7-1 antibody
  • dendritic-cell specific protein CREA7-4 antibody
  • FLJ37080 antibody
  • Gm638 antibody
  • JAML1_HUMAN antibody
  • junctional adhesion molecule antibody
  • Junctional adhesion molecule-like antibody
  • Junctional adhesion molecule-like precursor antibody
  • MGC118814 antibody
  • MGC118815 antibody
  • UNQ722/PRO1387 antibody
see all

Anti-JAML antibody images:

  Western blot - JAML antibody (ab67843)

Western blot - JAML antibody (ab67843)

All lanes : Anti-JAML antibody (ab67843) at 1/500 dilution

Lane 1 : JAML transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate

Lysates/proteins at 25 µg per lane.

Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution
developed using the ECL technique

Predicted band size : 44 kDa
Observed band size : 44 kDa

References for Anti-JAML antibody (ab67843)

ab67843 has not yet been referenced specifically in any publications.

Publishing research using ab67843? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"