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Overview

  • Product nameMCP1 protein (Active)See all MCP1 proteins and peptides ...
  • Protein descriptionRecombinant full length Mouse Monocyte Chemotactic Protein-1 (MCP-1)
  • Expression hostE. coli

    • Properties

  • Purification notesSterile filtered Greater than 99% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • FormLyophilised
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Concentration information loading...
  • Additional notesThe biological activity of this product was determined by its ability to chemoattract Balb/c mouse spleen MNCs using a concentration range of 0.1-10.0ng/ml.
  • Sequence notesRecombinant murine JE, also known as monocyte chemotactic protein (MCP-1), is a 13.8 kDa protein containing 125 amino acid residues. QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab9901 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Functional Studies FuncS: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab8101 and ab9899 and ab9899.

    • Protein info

    • Alternative names
        C-C motif chemokine 2CCL2CCL2_HUMAN
        Chemokine (C C motif) ligand 2Chemokine C C motif ligand 2GDCF 2GDCF-2GDCF2HC11HSMCR30JEMCAFMCP 1MCP-1MCP1MGC9434Monocyte chemoattractant protein 1Monocyte chemotactic and activating factorMonocyte chemotactic protein 1Monocyte secretory protein JESCYA2Small inducible cytokine A2Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je)Small inducible cytokine subfamily A (Cys Cys), member 2Small-inducible cytokine A2SMC CFSMC-CFSMCCF
      see all
  • FunctionChemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
  • Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
  • Post-translational
    modifications    Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession P13500 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for MCP1 protein (Active) (ab9901)

    ab9901 has not yet been referenced specifically in any publications.

    Publishing research using ab9901 ? Please let us know so that we can cite the reference in this datasheet

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    I would like to order MCP-1 protein and anti-MCP-1 antibody from "abcam". I would prefer to get it in liquid (reconstituted) form.

    I will be using antibody as a ...

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