JHDM1D peptide (ab37903)
- JHDM1Djmjc containing proteinJmjC domain-containing histone demethylation protein 1D
- jumonji containing proteinKDM7_HUMANkiaa1718Lysine-specific demethylase 7
Contains 1 JmjC domain.
Contains 1 PHD-type zinc finger.
The linker region is a critical determinant of demethylase specificity. It prevents the active site of JmjC to reach the target H3K9me2 when the PHD-type zinc finger binds to H3K4me3, while it favors selectivity toward H3K27me2.
References for JHDM1D peptide (ab37903)
ab37903 has not yet been referenced specifically in any publications.