This fast track antibody is not yet fully characterized. It is subject to these
terms and conditions
Anti-JMJD5 antibody (ab36104)
Overview
- Product nameAnti-JMJD5 antibodySee all JMJD5 primary antibodies ...
- DescriptionRabbit polyclonal to JMJD5
This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »
- Species reactivity
Predicted to work with: Mouse, Rat, Cow, Human - Immunogen
Synthetic peptide conjugated to KLH derived from within residues 350 to the C-terminus of Human JMJD5.
(Peptide available as ab36103.)
Properties
- FormLiquid
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4 -
Concentration information loading... - PurityImmunogen affinity purified
- Clonality Polyclonal
- IsotypeIgG
- Research Areas
Applications
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
- FunctionHistone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.
- Tissue specificityWeakly expressed in most cells. Highly expressed in breast cancer cells.
- Sequence similaritiesContains 1 JmjC domain.
- Cellular localizationNucleus.
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Database links
- Entrez Gene: 79831 Human
- Entrez Gene: 77035 Mouse
- Entrez Gene: 308976 Rat
- Omim: 611917 Human
- SwissProt: Q8N371 Human
- SwissProt: Q9CXT6 Mouse
- SwissProt: Q497B8 Rat
- Unigene: 145717 Human
- Unigene: 307239 Mouse
- Unigene: 22093 Rat
see all
Target information above from: UniProt accession
Q8N371
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- FLJ13798 antibodyJmjC domain-containing protein 5 antibodyJMJD5 antibody
- JMJD5 protein antibodyjumonji domain containing 5 antibodyJumonji domain-containing protein 5 antibodyKDM8_HUMAN antibodyLysine (K) specific demethylase 8 antibodyLysine-specific demethylase 8 antibody
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References for Anti-JMJD5 antibody (ab36104)
This product has been referenced in:
- Youn MY et al. JMJD5, a Jumonji C (JmjC) Domain-containing Protein, Negatively Regulates Osteoclastogenesis by Facilitating NFATc1 Protein Degradation. J Biol Chem 287:12994-3004 (2012). WB ; Human . Read more (PubMed: 22375008) »