This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

Properties

Applications

  • Application notesThis antibody gave a positive result in ELISA against the immunizing peptide (ab36103).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionHistone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.
    • Tissue specificityWeakly expressed in most cells. Highly expressed in breast cancer cells.
    • Sequence similaritiesContains 1 JmjC domain.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ13798 antibody
      • JmjC domain-containing protein 5 antibody
      • JMJD5 antibody
      • JMJD5 protein antibody
      • jumonji domain containing 5 antibody
      • Jumonji domain-containing protein 5 antibody
      • KDM8_HUMAN antibody
      • Lysine (K) specific demethylase 8 antibody
      • Lysine-specific demethylase 8 antibody
      see all

    References for Anti-JMJD5 antibody (ab36104)

    This product has been referenced in:
    • Youn MY  et al. JMJD5, a Jumonji C (JmjC) Domain-containing Protein, Negatively Regulates Osteoclastogenesis by Facilitating NFATc1 Protein Degradation. J Biol Chem 287:12994-3004 (2012). WB ; Human . Read more (PubMed: 22375008) »

    See 1 Publication for this product

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