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Overview
Product name
JMJD5 peptide
Protein description
Synthetic peptide derived from within residues 350 - 450 of Human JMJD5.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab36104 - JMJD5 antibody.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
Concentration information loading...
Applications
Application notes
This peptide can be used with studies using ab36104.
Protein info
Function
Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.
Tissue specificity
Weakly expressed in most cells. Highly expressed in breast cancer cells.
Sequence similarities
Contains 1 JmjC domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionQ8N371
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for JMJD5 peptide (ab36103)
ab36103 has not yet been referenced specifically in any publications.
Publishing research using ab36103? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"