Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Cell Biology >> Other Antibodies >> Other Antibodies
Overview
Product name
Anti-JPH1 antibody
See all JPH1 products (2) ...
Description
Rabbit polyclonal to JPH1
Tested applications
WB, ELISAmore details
Cross reactivity
Reacts with
Mouse, Rat, Human
Immunogen
A 15 amino acid synthetic peptide near the carboxy terminus of human JPH1 (AAI39833).
Positive control
293 cell lysate.
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
Affinity chromatography purified via peptide column
Clonality
Polyclonal
Isotype
IgG
Research areas
-
Western blot - JPH1 antibody (ab79062)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab79062 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use a concentration of 1 - 2 µg/ml.Predicted molecular weight: 72 kDa.
ELISA: Use at an assay dependent dilution.
Target
Relevance
JPH1 (Junctophilin 1) contributes to the stabilization of junctional membrane complexes, which are a common feature of all excitable cells and mediate cross talk between the cell surface and intracellular ion channels. It may act by anchoring the plasma membrane and endoplasmic/sarcoplasmic reticulum (ER/SR). It is composed of a C terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane.
Cellular localization
Cell membrane; Peripheral membrane protein (By similarity). Endoplasmic reticulum membrane; Single pass type IV membrane protein (By similarity). Sarcoplasmic reticulum membrane; Single pass type IV membrane protein. Note: Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic/sarcoplasmic reticulum membrane, while the N terminal part associates with the plasma membrane. In skeletal muscle cells, it is predominantly localized at the junction of the A and I bands.
Database links
- Entrez Gene: 56704 Human
- Entrez Gene: 57339 Mouse
- Entrez Gene: 297748 Rat
- Omim: 605266 Human
- SwissProt: Q9HDC5 Human
- SwissProt: Q9ET80 Mouse
- Unigene: 657367 Human
Anti-JPH1 antibody images:
Western blot - JPH1 antibody (ab79062)
Lane 1 : Anti-JPH1 antibody (ab79062) at 1 µg/ml
Lane 2 : Anti-JPH1 antibody (ab79062) at 2 µg/ml
Lane 1 : 293
cell lysate
Lane 2 : 293
cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size : 72 kDa
Observed band size : 72 kDa
References for Anti-JPH1 antibody (ab79062)
ab79062 has not yet been referenced specifically in any publications.
Publishing research using ab79062? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"