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Western blot - JPH1 antibody (ab79062)
(enlarge)
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Product Name
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JPH1 antibody
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See all JPH1 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to JPH1
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Immunogen
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A 15 amino acid synthetic peptide near the carboxy terminus of human JPH1 (AAI39833).
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Reacts with
(species key)
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Hu, Ms, Rat
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
WB: Use at a concentration of 1 - 2 µg/ml. Predicted molecular weight: 72 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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293 cell lysate.
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Cellular localization
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Cell membrane; Peripheral membrane protein (By similarity). Endoplasmic reticulum membrane; Single pass type IV membrane protein (By similarity). Sarcoplasmic reticulum membrane; Single pass type IV membrane protein. Note: Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic/sarcoplasmic reticulum membrane, while the N terminal part associates with the plasma membrane. In skeletal muscle cells, it is predominantly localized at the junction of the A and I bands.
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Research areas
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Cell Biology >> Other Antibodies >> Other Antibodies
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Relevance
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JPH1 (Junctophilin 1) contributes to the stabilization of junctional membrane complexes, which are a common feature of all excitable cells and mediate cross talk between the cell surface and intracellular ion channels. It may act by anchoring the plasma membrane and endoplasmic/sarcoplasmic reticulum (ER/SR). It is composed of a C terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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Affinity chromatography purified via peptide column
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this JPH1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for JPH1 antibody images, references, products related to ab79062 and other tools.
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JPH1 antibody images:
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 Western blot - JPH1 antibody (ab79062)
Lane 1 : JPH1 antibody (ab79062) at 1 µg/ml
Lane 2 : JPH1 antibody (ab79062) at 2 µg/ml
Lane 1 : 293
cell lysate
Lane 2 : 293
cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size : 72 kDa
Observed band size : 72 kDa
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Search PubMed (MEDLINE) for references to JPH1
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JPH1 antibody - more information
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Customer reviews (feedback) regarding JPH1 antibody |
Customer FAQs regarding JPH1 antibody |
Protocols for JPH1 antibody |
Price and availability of products related to JPH1 antibody |
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JPH1 antibody - related products:
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JPH1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about JPH1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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