Jarid1C / SMCX peptide (ab35501)

Product Name 

Jarid1C / SMCX peptide

Product type 

Proteins and Peptides

Peptide 

Synthetic peptide derived from within residues 1500 to the C-terminus of Human Jarid1C / SMCX.This peptide was used as an immunogen for ab34718 - Jarid1C / SMCX antibody.

Research areas 

Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Jumonji containing proteins
Chromatin and Nuclear Signaling >> Transcription >> Co-factors
Chromatin and Nuclear Signaling >> Transcription >> Other factors
Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Co-activators/co-repressors

Relevance 

KDM5C / JARID1C / SMCX is expressed in a variety of tissues and it's highest levels are found in skeletal and brain extracts. Defects in SMCX are the cause of X-linked mental retardation (XLMR). Etiologically, mental retardation is a very heterogeneous condition that involves environmental, stochastic and/or genetic factors.

KDM5C specifically demethylates di and tri methyl histone H3 at K4.

Storage buffer 

Preservative: None
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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