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Products:Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> Leucine Zipper
Overview
Product name
Anti-JunB antibody
See all JunB products (9) ...
Description
Rabbit polyclonal to JunB
Specificity
ab28838 recognises JunB.
Tested applications
IHC-P, ELISA, IPmore details
Cross reactivity
Reacts with
Mouse, Human
Immunogen
Synthetic non-phosphopeptide derived from human JunB around the phosphorylation site of Serine 79.
Positive control
Breast carcinoma.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, 150% Sodium chloride, PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
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Immunohistochemistry (Paraffin-embedded sections) - JunB antibody (ab28838)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab28838 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: 1/50 - 1/100.
ELISA
ELISA: 1/10000ELISA: 1/10000
IP: Use at an assay dependent dilution.
Target
Relevance
The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.
Cellular localization
Nuclear
Alternative names
- Activator protein 1 antibody
- AP 1 antibody
- AP1 antibody
see all
Database links
- Entrez Gene: 3726 Human
- Entrez Gene: 16477 Mouse
- Omim: 165161 Human
- SwissProt: P17275 Human
- SwissProt: P09450 Mouse
- Unigene: 25292 Human
Anti-JunB antibody images:
Immunohistochemistry (Paraffin-embedded sections) - JunB antibody (ab28838)
Immunohistochemical analysis of paraffin embedded breast carcinoma using 1/50 JunB (Ab-1) Antibody (ab28838). Left: Untreated sample Right: Sample preincubated with synthesized peptide (negative control).
References for Anti-JunB antibody (ab28838)
ab28838 has not yet been referenced specifically in any publications.
Publishing research using ab28838? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"