Anti-K Cadherin/CDH6 antibody (ab197845)
Key features and details
- Rabbit polyclonal to K Cadherin/CDH6
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-K Cadherin/CDH6 antibody
See all K Cadherin/CDH6 primary antibodies -
Description
Rabbit polyclonal to K Cadherin/CDH6 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Fusion protein corresponding to Human K Cadherin/CDH6 (internal sequence). (BC000019)
Database link: P55285-2 -
Positive control
- HeLa, A549 and HT29 cell lysates; Human liver cancer tissue lysate. Human brain tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab197845 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500 - 1/2000. Predicted molecular weight: 74 kDa.
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IHC-P |
1/50 - 1/200.
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Notes |
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WB
1/500 - 1/2000. Predicted molecular weight: 74 kDa. |
IHC-P
1/50 - 1/200. |
Target
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Function
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. -
Tissue specificity
Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. -
Sequence similarities
Contains 5 cadherin domains. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 1004 Human
- Entrez Gene: 12563 Mouse
- Entrez Gene: 25409 Rat
- Omim: 603007 Human
- SwissProt: P55285 Human
- SwissProt: P97326 Mouse
- SwissProt: P55280 Rat
- Unigene: 171054 Human
see all -
Alternative names
- CAD6 antibody
- CADH6_HUMAN antibody
- Cadherin 6 antibody
see all
Images
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All lanes : Anti-K Cadherin/CDH6 antibody (ab197845) at 1/500 dilution
Lane 1 : HeLa cell lysate
Lane 2 : A549 cell lysate
Lane 3 : Human liver cancer tissue lysate
Lane 4 : HT29 cell lysate
Lysates/proteins at 40 µg per lane.
Predicted band size: 74 kDa
Exposure time: 2 minutesGel: 8%SDS-PAGE
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Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling K Cadherin/CDH6 with ab197845 at 1/50 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab197845 has been referenced in 2 publications.
- Stucky A et al. Molecular Characterization of Differentiated-Resistance MSC Subclones by Single-Cell Transcriptomes. Front Cell Dev Biol 10:699144 (2022). PubMed: 35356283
- Karthikeyan S et al. Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface. Oncotarget 7:69871-69882 (2016). WB, IHC . PubMed: 27563818