![Western blot - NCOA2 antibody [2615C1a] (ab53544) image](#ncoa.jpg)
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Overview
Product name
Anti-KAT13C / NCOA2 antibody [2615C1a]
See all KAT13C / NCOA2 products (11) ...
Description
Mouse monoclonal [2615C1a] to KAT13C / NCOA2
Tested applications
WB, Dot Blotmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment of NCOA2 (Human)
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS
Concentration
Concentration information loading...
Purity
Protein G purified
Purification notes
Purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG depleted (pproximately 95%) fetal bovine serum
Clonality
Monoclonal
Clone number
2615C1a
Isotype
IgG1
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Epigenetics and Nuclear Signaling >> Transcription >> Mediator Complex
Epigenetics and Nuclear Signaling >> Transcription >> Other factors
Epigenetics and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Co-activators/co-repressors
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Western blot - NCOA2 antibody [2615C1a] (ab53544)
![Western blot - NCOA2 antibody [2615C1a] (ab53544) image](/ps/datasheet/Images/53/ab53544/ncoa.jpg)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab53544 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at an assay dependent dilution. Predicted molecular weight: 159 kDa.
Dot: Use at an assay dependent dilution.
Target
Relevance
Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcriptional activity of the nuclear receptor with which they associate. One such coactivator is KAT13C / nuclear receptor coactivator 2 (NCOA2), also termed Glucocorticoid receptor-interacting protein 1 (GRIP1).
Cellular localization
Nuclear
Alternative names
- glucocorticoid receptor interacting protein 1 antibody
- GRIP 1 antibody
- GRIP1 antibody
see all
Database links
- Entrez Gene: 10499 Human
- Omim: 601993 Human
- SwissProt: Q15596 Human
- Unigene: 446678 Human
Anti-KAT13C / NCOA2 antibody [2615C1a] images:
Western blot - NCOA2 antibody [2615C1a] (ab53544)
Anti-KAT13C / NCOA2 antibody [2615C1a] (ab53544) + Immunized recombinant protein
Predicted band size : 159 kDa
Observed band size : 38 kDa (why is the actual band size different from the predicted?)
The molecular weight of the band on the western blot does not correspond to the molecular weight of the natural protein as the immunizing recombinant fragment protein was used as the test antigen
References for Anti-KAT13C / NCOA2 antibody [2615C1a] (ab53544)
ab53544 has not yet been referenced specifically in any publications.
Publishing research using ab53544? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"