Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Soluble in water to 25 mM and in DMSO to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
John GW et al. KC 12291: an atypical sodium channel blocker with myocardial antiischemic properties. Cardiovasc Drug Rev22:17-26 (2004).
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Decking UK et al. Cardioprotective actions of KC 12291. I. Inhibition of voltage-gated Na+ channels in ischemia delays myocardial Na+ overload. Naunyn Schmiedebergs Arch Pharmacol358:547-53 (1998).
Read more (PubMed: 9840423) »
Hartmann M et al. Cardioprotective actions of KC 12291. II. Delaying Na+ overload in ischemia improves cardiac function and energy status in reperfusion. Naunyn Schmiedebergs Arch Pharmacol358:554-60 (1998).
Read more (PubMed: 9840424) »