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Products:Neuroscience >> Neurotransmission >> Receptors / Channels >> Potassium Channels
Overview
Product name
Anti-KCNG1 antibody
See all KCNG1 products (2) ...
Description
Rabbit polyclonal to KCNG1
Specificity
This antibody recognizes KCNG1
Tested applications
ELISA, WBmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Mouse, Rat, Cow, Pig
Immunogen
A synthetic peptide corresponding to a region of Human KCNG1
Positive control
HepG2 cell lysate
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 2% Sucrose, PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Neurotransmission >> Receptors / Channels >> Potassium Channels
-
Western blot - KCNG1 antibody (ab49063)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab49063 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
- 1 Image
WB
Application notes
ELISA: Use at an assay dependent dilution. ELISA titre using peptide based assay was 1:62500.
WB: Use at a concentration of 0.25 µg/ml. Detects a band of approximately 58 kDa (predicted molecular weight: 56 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
KCNG1 is a member of the potassium channel, voltage-gated, subfamily G. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene is abundantly expressed in skeletal muscle. Alternative splicing results in at least two transcript variants encoding distinct isoforms.
Cellular localization
Membrane; multi-pass membrane protein
Alternative names
- K13 antibody
- KCNG antibody
- kH2 antibody
see all
Database links
- Entrez Gene: 3755 Human
- Entrez Gene: 241794 Mouse
- Entrez Gene: 296395 Rat
- Omim: 603788 Human
- SwissProt: Q86Y85 Human
- SwissProt: Q9UIX4 Human
- SwissProt: A2BDX4 Mouse
- Unigene: 118695 Human
see all
Anti-KCNG1 antibody images:
Western blot - KCNG1 antibody (ab49063)
Lane 1 : Marker
Lane 2 : Anti-KCNG1 antibody (ab49063) at 0.25 µg/ml
Lane 1 : As above
Lane 2 : HepG2 cell lysate at 10 µg with 5% skimmed milk in PBS.
Secondary
Lane 2 : HRP conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size : 56 kDa
Observed band size : 58 kDa (why is the actual band size different from the predicted?)
Gel concentration: 12%
References for Anti-KCNG1 antibody (ab49063)
This product has been referenced in:
- O'Connell DJet al. Integrated protein array screening and high throughput validation of 70 novel neural calmodulin binding proteins. Mol Cell Proteomics : (2010). WB; Mouse.Read more (PubMed: 20068228) »
See 1 publication for this product
Publishing research using ab49063? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"