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Overview

  • Product nameKCNS3 protein (His-DHFR tag)
  • Protein descriptionRecombinant fragment of Human KCNS3 (amino acids 10-147) with N terminal His-DHFR tag. Predicted MWt 16.4 kDa excluding tag (Uniprot ID = Q9BQ31).
  • Uniprot accessionQ9BQ31
  • Molecular weight16.400kDa
  • Protein length138 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 95 % Purified via His tag
  • Purification notesPurity was determined to be >95% by SDS-PAGE.
  • FormLyophilised:Reconstitute with water to desired concentration.
  • Storage instructionsShipped at 4°C. Store at -20ºC.
  • Storage bufferConstituents: 0.32% Tris HCl, 0.58% Sodium chloride
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab127651 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        Delayed rectifier K(+) channel alpha subunit 3Delayed rectifier K+ channel alpha subunit 3Delayed-rectifier K(+) channel alpha subunit 3
        KCNS 3Kcns3KCNS3_HUMANKV 9.3KV9.3MGC9481Potassium voltage gated channel delayed rectifier protein S3Potassium voltage gated channel delayed rectifier subfamily S member 3Potassium voltage gated channel subfamily S member 3Potassium voltage-gated channel subfamily S member 3Shab related delayed rectifier K+ channel alpha subunit 3Voltage gated potassium channel subunit Kv9.3Voltage-gated potassium channel subunit Kv9.3
      see all
  • FunctionPotassium channel subunit. Modulates channel activity and reduces the ion flow.
  • Tissue specificityDetected in most tissues, but not in peripheral blood lymphocytes. The highest levels of expression are in lung.
  • Sequence similaritiesBelongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily.
  • DomainThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localizationCell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.

    • Target information above from: UniProt accession Q9BQ31 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for KCNS3 protein (His-DHFR tag) (ab127651)

    ab127651 has not yet been referenced specifically in any publications.

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