Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
This fast track antibody is not yet fully characterised. It is subject to these terms and conditions
Overview
Product name
Anti-KDM3B / JMJD1B antibody
See all KDM3B / JMJD1B products (5) ...
Description
Rabbit polyclonal to KDM3B / JMJD1B
This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »
Cross reactivity
Predicted to work with
Mouse, Human
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 900 - 1000 of Human JMJD1B.
(Peptide available as ab32467.)
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS. pH 7.4
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Methylation >> Lysine demethylation
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Jumonji containing proteins
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> Zinc Finger
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Methylation
Applications
Application notes
This antibody gave a positive result in ELISA against the immunizing peptide (ab32467).
Not yet tested in other applications.
Target
Function
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
Tissue specificity
Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.
Sequence similarities
Belongs to the JHDM2 histone demethylase family.
Contains 1 JmjC domain.
Domain
Leu-Xaa-Xaa-Leu-Leu (LXXLL) motifs are known to mediate the association with nuclear receptors.
Cellular localization
Nucleus.
Target information above from: UniProt accessionQ7LBC6
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 5qNCA antibody
- C5orf7 antibody
- JHDM2B antibody
see all
Database links
- Entrez Gene: 51780 Human
- Omim: 609373 Human
- SwissProt: Q7LBC6 Human
- SwissProt: Q9BVH6 Human
- SwissProt: Q3TQV8 Mouse
- SwissProt: Q3UI14 Mouse
- SwissProt: Q6ZPY7 Mouse
- Unigene: 483486 Human
see all
References for Anti-KDM3B / JMJD1B antibody (ab31209)
ab31209 has not yet been referenced specifically in any publications.
Publishing research using ab31209? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"