KDM3B / JMJD1B antibody (ab31209)

Product Name 

KDM3B / JMJD1B antibody

Product type 

Primary antibodies

Description 

Rabbit polyclonal to KDM3B / JMJD1B

Immunogen 

Synthetic peptide conjugated to KLH derived from within residues 900 - 1000 of Human JMJD1B.

(Peptide available as ab32467.)

Predicted to react 
(species key)

Hu, Ms
(Due to sequence homology)

Abreviews 

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Application notes 
(see key)

Recommended dilutions
This antibody gave a positive result in ELISA against the immunizing peptide (ab32467).
Not yet tested in other applications.

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Methylation >> Lysine demethylation
Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Jumonji containing proteins
Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> Zinc Finger

Relevance 

KDM3B / JHDM2B / JMJD1B is a histone demethylase responsible for demethylating mono methyl histone H3 at K9.

JMJD1B contains a highly-conserved C-terminus containing a zinc finger with the unique spacing Cys-X2-Cys-X7-His-X2-Cys-X2-Cys-X4-Cys-X2-Cys and a jmjC domain. It plays an important role in histone demethylation and may be a candidate for tumor suppressors.

Database links 

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS. pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

0.300 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

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