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Western blot - JMJD2A antibody - ChIP Grade (ab24545)
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Product Name
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KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade
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See all KDM4A / JHDM3A / JMJD2A antibodies (5)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to KDM4A / JHDM3A / JMJD2A - ChIP Grade
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Immunogen
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Recombinant fragment, corresponding to amino acids 592-720 of Human JMJD2A
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Reacts with
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Hu
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Predicted to react
(species key)
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Rat
(Due to sequence homology)
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Tested applications
(see key)
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ChIP, IP, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ChIP: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
WB: 1/2000. Detects a band of approximately 130 kDa (predicted molecular weight: 120 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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HeLa cell nuclear lysate.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> ChIP'ing antibodies >> ChIP'ing antibodies
Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Methylation >> Lysine demethylation
Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Jumonji containing proteins
Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Co-activators/co-repressors
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Relevance
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The JHDM3A/JMJD2A gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with a JmjC domain, a JmjN domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. KDM4A specifically demethylates histone H3 at K9 and K36.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade images, references, products related to ab24545 and other tools.
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KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade images:
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References for KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade (ab24545)
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This product has been used in: (two most recent references)
Aslan JE et al. Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis. Mol Cell 34:497-509 (2009). ChIP; Human. PubMed: 19481529
Klose RJ et al. The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Nature : (2006). PubMed: 16732292
See all 3 publication references for this product.
If you publish research using ab24545 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to KDM4A / JHDM3A / JMJD2A
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KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade - more information
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Customer reviews (feedback) regarding KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade |
Customer FAQs regarding KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade |
Protocols for KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade |
Price and availability of products related to KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade |
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KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade - related products:
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KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade - other tools:
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Contact Abcam with a Technical Enquiry about KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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Western blot - JMJD2A antibody - ChIP Grade (ab24545)