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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - KDM5B / PLU1 / Jarid1B antibody (ab84883)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - KDM5B / PLU1 / Jarid1B antibody (ab84883)
(enlarge)


Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - KDM5B / PLU1 / Jarid1B antibody (ab84883)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - KDM5B / PLU1 / Jarid1B antibody (ab84883)
(enlarge)


Product Name 

KDM5B / PLU1 / Jarid1B antibody

 

See all KDM5B / PLU1 / Jarid1B antibodies (5)...

Product type 

Primary antibodies

Description 

Rabbit polyclonal to KDM5B / PLU1 / Jarid1B

Immunogen 

Synthetic peptide corresponding to a region between residue 1494 and 1544 of human KDM5B/ PLU1/ Jarid1B (accession number: NP_006609.3)

Reacts with 
(species key)

Hu

Tested applications 
(see key)

IHC-P


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

Likely to work with frozen sections.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Human Controls: Breast Carcinoma, Prostate Carcinoma

Cellular localization 

Nuclear

Research areas 

Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Jumonji containing proteins
Chromatin and Nuclear Signaling >> Transcription >> Co-factors
Chromatin and Nuclear Signaling >> Transcription >> Other factors
Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Co-activators/co-repressors

Relevance 

KDM5B / PLU1 / Jarid1b is a novel breast cancer associated nuclear protein containing highly conserved domains, including JmjC and JmjN motifs. KDM5B interacts with Brain Factor 1 (BF1) and Pax9. KDM5B specifically demethylates mono, di and tri methyl histone H3 at K4.

 

Alternative names KDM5B / PLU1 / Jarid1B antibody (ab84883)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

10765    (Human)

Omim

    

605393    (Human)

SwissProt

    

Q9UGL1    (Human)

Unigene

    

443650    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Immunogen affinity purified

Storage buffer 

Preservative: 0.09% Sodium Azide
Constituents: 0.1% BSA, Tris buffered saline

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Purified using an epitope specific to KDM5B / PLU1 / Jarid1B immobilized on solid support.

Form 

Liquid

Storage instructions 

Store at +4°C.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this KDM5B / PLU1 / Jarid1B antibody is on this datasheet. But please do contact us if you would like any reassurance!


See below for KDM5B / PLU1 / Jarid1B antibody images, references, products related to ab84883 and other tools.

 

KDM5B / PLU1 / Jarid1B antibody images:

Product image  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - KDM5B / PLU1 / Jarid1B antibody (ab84883)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - KDM5B / PLU1 / Jarid1B antibody (ab84883)

Detection of Human Jarid1B in a formalin-fixed paraffin-embedded section of human prostate carcinoma by Immunohistochemistry using ab84883 at a dilution of 1:500. Detection: DAB staining.

 

Product image  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - KDM5B / PLU1 / Jarid1B antibody (ab84883)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - KDM5B / PLU1 / Jarid1B antibody (ab84883)

Detection of Human Jarid1B in a formalin-fixed paraffin-embedded section of human breast carcinoma by Immunohistochemistry using ab84883 at a dilution of 1:250. Detection: DAB staining.

 
 

Search PubMed (MEDLINE) for references to KDM5B / PLU1 / Jarid1B

 

KDM5B / PLU1 / Jarid1B antibody - more information

Customer reviews (feedback) regarding KDM5B / PLU1 / Jarid1B antibody

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Protocols for KDM5B / PLU1 / Jarid1B antibody

Price and availability of products related to KDM5B / PLU1 / Jarid1B antibody

 

KDM5B / PLU1 / Jarid1B antibody - related products:

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Prostate tumor (human): adenocarcinoma tissue slides

 

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