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Product Name 

KIR2DL3 antibody [190IIC311]

 

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Product type 

Primary antibodies

Description 

Mouse monoclonal [190IIC311] to KIR2DL3

Immunogen 

Recombinant full length protein (Human).

Reacts with 
(species key)

Hu

Epitope 

Ab14825 reacts with extracellular domain of the KIR2DL3

Tested applications 
(see key)

ELISA, Flow Cyt, WB


Abreviews 

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Application notes 
(see key)

Recommended dilutions
ELISA: 1/1000.
Flow Cyt: Use 5 - 10µg for 1 x 106 cells.
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Human peripheral blood mononuclear cells or natural killer cells.

Cellular localization 

Type I membrane protein

Research areas 

Immunology >> Immunoglobulins >> Receptors

Relevance 

KIR2DL3 is a member of the killer cell immunoglobulin-like receptor (KIR) family. The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells. They are involved in recognition of either MHC class I molecules or unknown ligand on target cells and inhibit cytotoxic activities.

 

Alternative names KIR2DL3 antibody [190IIC311] (ab14825)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

3804    (Human)

GeneCard

    

GC19P059737    (Human)

Omim

    

604938    (Human)

SwissProt

    

P43628    (Human)

Unigene

    

654605    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

190IIC311

Myeloma 

P3-X63 Ag8.3

Isotype 

IgG2a

Light chain type 

kappa

Purity 

Protein G purified

Storage buffer 

Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this KIR2DL3 antibody [190IIC311] is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to KIR2DL3

 

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