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Products:Immunology >> Immunoglobulins >> Receptors
Overview
Product name
Anti-KIR2DL3 antibody [CD158b]
See all KIR2DL3 products (3) ...
Description
Mouse monoclonal [CD158b] to KIR2DL3
Specificity
Reacts with an extracellular domain of KIR2DL3 but does not recognise related KIR2DL family members KIR2DL1 and KIR2DS4.
Tested applications
WB, Flow Cytmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein: human KIR2DL3.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein G purified
Purification notes
Purified by affinity chromatography from tissue culture supernatant.
Clonality
Monoclonal
Clone number
CD158b
Myeloma
P3x63-Ag8.653
Isotype
IgG2a
Research areas
Applications
Show applications key
Our Abpromise guarantee covers the use of ab21647 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
Flow Cyt
Application notes
Flow Cyt: Use 10µl for 106 cells in 100µl (hence 1:10 dilution).
WB: Use at an assay dependent dilution. Predicted molecular weight: 38 kDa.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
KIR2DL3 is a member of the killer cell immunoglobulin-like receptor (KIR) family. The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells. They are involved in recognition of either MHC class I molecules or unknown ligand on target cells and inhibit cytotoxic activities.
Cellular localization
Type I membrane protein
Alternative names
- CD158b antibody
- GL183 antibody
- Killer Cell Immunoglobulin Like Receptor 2DL3 antibody
see all
Database links
- Entrez Gene: 3804 Human
- Omim: 604938 Human
- SwissProt: P43628 Human
- Unigene: 654605 Human
References for Anti-KIR2DL3 antibody [CD158b] (ab21647)
ab21647 has not yet been referenced specifically in any publications.
Publishing research using ab21647? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"