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Western blot - KLF6 antibody (ab45302)
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Product Name
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KLF6 antibody
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See all KLF6 antibodies (3)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to KLF6
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Immunogen
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Recombinant Human KLF6 protein fragment with an N-terminal fusion tag.
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Reacts with
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Hu
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Tested applications
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at an assay dependent dilution. Predicted molecular weight: 31 kDa.
This antibody was tested using a recombinant KLF6 protein fragment (immunogen) only. We have no data on detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> Krueppel like factor
Chromatin and Nuclear Signaling >> Transcription >> Krueppel like factor
Stem Cells >> Hematopoietic Progenitors >> Intracellular Molecules
Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> Developmental Families >> Other
Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> Zinc Finger
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Relevance
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KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this KLF6 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for KLF6 antibody images, references, products related to ab45302 and other tools.
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KLF6 antibody images:
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 Western blot - KLF6 antibody (ab45302)
All lanes : KLF6 antibody (ab45302) at 1/1000 dilution
Lane 1 : Recombinant KLF6 protein (15µg)
Lane 2 : Negative control protein (15µg)
Predicted band size : 31 kDa
Western blot developed using a DAB staining kit.
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Search PubMed (MEDLINE) for references to KLF6
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KLF6 antibody - more information
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Customer reviews (feedback) regarding KLF6 antibody |
Customer FAQs regarding KLF6 antibody |
Protocols for KLF6 antibody |
Price and availability of products related to KLF6 antibody |
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KLF6 antibody - related products:
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KLF6 antibody - other tools:
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Contact Abcam with a Technical Enquiry about KLF6 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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