Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> Kallikreins
Overview
Product name
Anti-Kallikrein 4 antibody
See all Kallikrein 4 products (5) ...
Description
Rabbit polyclonal to Kallikrein 4
Tested applications
WB, ELISAmore details
Cross reactivity
Reacts with
Mouse, Human
Immunogen
Synthetic peptide from the center region of human Kallikrein 4 conjugated to KLH
Positive control
Mouse brain tissue lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Ammonium Sulphate Precipitation
Purification notes
ab71234 is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Clonality
Polyclonal
Isotype
IgG
Research areas
Cell Biology >> Proteolysis / Ubiquitin >> Proteolytic enzymes >> Serine protease >> Kallikreins
Cancer >> Invasion/microenvironment >> ECM >> Extracellular matrix >> Kallikreins
Signal Transduction >> Cytoskeleton / ECM >> Extracellular Matrix >> ECM Enzymes >> Kallikreins
-
Western blot - Kallikrein 4 antibody (ab71234)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab71234 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/100 - 1/500.Detects a band of approximately 27 kDa (predicted molecular weight: 27 kDa).
ELISA
ELISA: 1/1000ELISA: 1/1000
Target
Tissue specificity
Expressed in prostate.
Involvement in disease
Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) [MIM:204700]. AI2A1 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel.
Sequence similarities
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain.
Cellular localization
Secreted.
Target information above from: UniProt accessionQ9Y5K2
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- EC 3.4.21.- antibody
- Kallikrein like protein 1 antibody
- 7S nerve growth factor alpha chain antibody
see all
Database links
- Entrez Gene: 9622 Human
- Entrez Gene: 56640 Mouse
- Omim: 603767 Human
- SwissProt: Q9Y5K2 Human
- SwissProt: P00757 Mouse
- Unigene: 218366 Human
Anti-Kallikrein 4 antibody images:
Western blot - Kallikrein 4 antibody (ab71234)
Anti-Kallikrein 4 antibody (ab71234) at 1/100 dilution + mouse brain tissue lysate at 12.5 µg
Predicted band size : 27 kDa
Observed band size : 27 kDa
Additional bands at : 50 kDa. We are unsure as to the identity of these extra bands.
References for Anti-Kallikrein 4 antibody (ab71234)
ab71234 has not yet been referenced specifically in any publications.
Publishing research using ab71234? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"